We enable Drs to safely inject medicines into cells to create new treatments for cancer and other severe diseases. NAVAN Technologies, Inc. is an enabling technology company commercializing a novel non-viral delivery platform to radically accelerate genetic engineering of human stem & primary cells. The patented NanoStraw technology provides direct intracellular access into hard-to-transfect stem & primary human cells for efficacious delivery of any cargo. By using a physical, non-perturbative mechanism for delivery, the challenges of viral-based cell manufacturing (time, cost and technical difficulties) are eliminated, resulting in fewer, faster operational steps. For more information on NAVAN, please visit www.navanbio.com.

62 similar entities Type: Startup Activities: deeptech Technologies: Synthetic Biology

Faircraft develops a highly sustainable, lab-grown alternative to animal leather. Faircraft develops a highly sustainable, lab-grown alternative to animal leather, based on advanced tissue engineering and material science techniques.

59 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology New Materials

Creating Tomorrow's Immunotherapies NXI therapeutics focuses on the research and development of a new generation of selective immunosuppressive drugs for autoimmune diseases and transplantations - with objectives of high efficacy, good safety without adverse effects as seen with conventional immunosuppressants.

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Exploiting a proprietary tech platform to develop biomolecular tools for therapeutic & synthetic biology applications PartitionBioTM Exploiting a novel proprietary technology platform to develop biomolecular tools for the use in therapeutic and synthetic biology applications.

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SmartCella is a global drug delivery company providing first-in-class delivery platforms for targeted therapies. SmartCella is a global drug delivery company providing first-in-class delivery platforms for targeted therapies, including the main technology, the FDA 510(k)-cleared Extroducer® for localized endovascular delivery to hard-to-reach organs and tissues, and a proprietary stem cell platform for the delivery of mRNA therapeutics.

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Affirma Biotech develops new products to overcome the challenge of Multi Drug Resistant and Chronic Infections Affirma Biotech is a start-up company specialized in the discovery and development of new anti-infective drugs via immunomodulation.

165 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Aesyra SA is a spin-off of EPFL created in November 2017 in close collaboration with medical experts from the Clinique Universitaire de Médecine Dentaire de Genève (CUMD). Aesyra’s mission is to develop, manufacture and commercialize a medical device able to accurately monitor the jaw activity of the patient during sleep and provide an active bio-feedback to reduce teeth grinding without waking-up the patient.

69 similar entities Type: Startup Activities: manufacturing healthtech deeptech Technologies: Synthetic Biology

We are developing first-in-class small molecules to improve mitochondrial function and reduce chronic inflammation. We are developing first-in-class small molecules against a novel target to improve mitochondrial function and reduce chronic inflammation to treat age-related diseases.

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Procavea Biotech is on a mission to solve the problem of delivering RNA-based drugs to non-liver tissues. At Procavea we're developing nonviral protein cages as carriers for the delivery of RNA Therapeutics to specific tissues in the body. Protein Engineering and RNA Delivery

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AGV Discovery offers services in chemistry, cell biology, in vitro screening, rational drug design, outsourcing and consultancy. AGV Discovery is a pharmaceutical company that specializes in the rational design and early development of drug candidates.

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PulseSight is an ophthalmology drug development company developing disruptive non-viral gene therapies with minimally-invasive delivery technology to treat major eye diseases. Our mission is to develop life-changing solutions for patients with diseases leading to sight loss.

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Distribution of medical devices including superpulsed therapy lasers and PEMF therapy instruments Superpulsed therapeutic lasers: Lumix 2 Series, Superpulsed + CW therapeutic lasers: Lumix 3 Series, Superpulsed + CW therapeutic lasers: Lumix 4 Series, Lumix Lasers, superpulsed lasers, therapeutic lasers, medical devices, and technology

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Unlocking the therapeutic potential of AAT AATec Medical GmbH is a biotech company developing a product platform based on recombinant alpha-1 antitrypsin (AAT) for the treatment of inflammatory diseases, virus infections and rare diseases. The first product candidate is a novel AAT formulation for inhalation to treat emerging inflammatory diseases of the lung and respiratory virus infections.

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Pioneering medicine by harnessing metabolism in the DNA damage response One-carbon therapeutics AB is developing first-in-class MTHFD1/2 inhibitors of one-carbon metabolism, representing a novel way of attacking the DNA damage response (DDR) and targeting cancer.

60 similar entities Type: Startup Activities: deeptech cleantech greentech Technologies: Synthetic Biology Decarbonization

The IV drug-delivery expert Technoflex is the independent leader in the design, production and commercialization of I.V. drug delivery bags (standard or customized) and connectors with FDA and EMEA references. With a devoted R&D team, Technoflex offers a specific high value opportunity of taylored products to its partners.

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Nuuron is developing a Digital Drug to treat Alzheimer’s Disease. Nuuron is a VC backed, clinical stage neurotech company that develops the Memory-Pacemaker, a non-invasive, photonic neurostimulation to re-enable patients with Alzheimer's Disease to store and recall memories again.

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Delivering tomorrow's genetic medicines, todayTM NanoVation Therapeutics is a pioneer in the design and creation of lipid nanoparticles (LNPs) for nucleic acid delivery. The company’s LNP technologies aim to overcome the limitations of existing nucleic acid delivery approaches, including the ability to target tissues outside the liver (extrahepatic delivery). NanoVation’s lead technology is its proprietary long-circulating LNP (lcLNPTM) platform, which enables functional nucleic acid delivery to extrahepatic cell types and has demonstrated an improved therapeutic index in preclinical studies. NanoVation partners with leading pharmaceutical and biotech companies develop genetic medicines for previously untreatable diseases. NVTx is delivering tomorrow's genetic medicines, …

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CytoTronics no longer sells or supports the Pixel System and associated plates and software. The intellectual property of CytoTronics has been acquired by Axion BioSytems. Visit Axionbio.com to see what’s new! Electrophysiology, CMOS, Phenotypic Screening, Electrochemistry, Cell measurement, and Cell manipulation

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Syntropic transforms depression care with light-based treatment Syntropic is developing HAVEN, a non-invasive brain stimulation device that restores neuroplasticity to treat depression. By delivering precise pulsed light stimulation, HAVENTM activates microglia, the brain’s immune cells, to remodel extracellular structures that block neuroplasticity. Syntropic’s technology is based on pioneering discovery by our scientific co-founders Prof. Sandra Siegert and Dr. Alessandro Venturino at ISTA, Institute of Science and Technology Austria.

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Biomade Peptides We believe that in the near future peptides have found their way into new markets and are a well-known feed stock for better products in life sciences and beyond. NUMAFERM supports you in these developments – from discovery to commercial production.

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Immunic (Nasdaq: IMUX) is a late-stage biotechnology company developing novel oral therapies for neurologic diseases. Immunic, Inc. (Nasdaq: IMUX) is a late-stage biotechnology company pioneering the development of novel oral therapies for neurologic diseases. Privacy Policy: https://imux.com/privacy-policy/

100 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

The Precision Vaccines Company Belyntic creates novel vaccines for viral diseases with unmet medical need. We have developed and validated a new platform technology, that generates self-adjuvant synthetic long peptides for a safe and durable induction of cellular immunity. Drug development, Cellular immunity, and Platform technology

260 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Platelet Secretome : a New Therapeutic Strategy Against Neurodegeneration InVenis Biotherapies is a biotech compagny, spin-off from academic laboratory U1172 and Taipei Medical University, developping innovative regenerative therapies based on blood platelet. Thanks to the high therapeutic potential of our product, we target the most severe diseases involving cell death, as the amyotrophic lateral sclerosis.

158 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

We develop an innovative subcutaneous formulation for anticancer highly potent API to unlock their full potential. IMESCIA is a preclinical-stage company developing a new formulation for anticancer highly potent APIs to unlock their full potential.

61 similar entities Type: Startup Activities: deeptech biotech Technologies: SaaS

A WuXi Advanced Therapies company, based in Oxford, UK. OXGENE, a WuXi Advanced Therapies (WuXi ATU) company, based in Oxford, UK, provides cell and gene therapy pioneers around the world with the technologies, automation platforms and service solutions they need to come first in the race to deliver ground-breaking therapeutics. OXGENETM is headquartered in Oxford, UK. For additional information, please visit our website. PRODUCTS: Largest collection of standardised plasmids on the market and SERVICES: DNA Services, Protein Production Services, Virus Services, Cell Line Development Services.

113 similar entities Type: Startup Activities: deeptech Technologies: Synthetic Biology

Global experts in nanotechnology and drug particle engineering Nanoform is an innovative nanoparticle medicine enabling company. Nanoform works together with pharma and biotech partners globally to provide hope for patients in developing new and improved medicines utilizing Nanoform’s platform technologies. The company focuses on reducing clinical attrition and on enhancing drug molecules’ performance through its nanoforming technologies and formulation services. Nanoform’s capabilities include GMP manufacturing, and its services span the small to large molecule development space with a focus on solving key issues in drug solubility and bioavailability and on enabling novel drug delivery applications.

59 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Fast, integrated structural biology for drug discovery — MX, cryo-EM and biophysics. ALPX is an innovative structural biology company spun out of EMBL Grenoble, supporting pharma and biotech partners in structure-based drug discovery. We provide automated MX, cryo-EM and biophysics services to help teams move faster from protein to structure to decision. Our platforms can be tailored to each project and, when useful, run in parallel to identify the best path with speed and confidence. Our expertise covers small molecules, biologics, membrane proteins and targeted protein degradation complexes, from high-resolution structure determination to mechanistic interpretation. Speed, flexibility and transparency define …

85 similar entities Type: Startup Activities: deeptech Technologies: Synthetic Biology

Advanced Biomaterials for Regenerative Medicine Tensive is a biomedical company developing advanced biomaterials for regenerative medicine applications, with a current focus on reconstructive surgery after breast cancer.

77 similar entities Type: Startup Activities: deeptech healthtech Technologies: New Materials Synthetic Biology

Dermo-innovation Feeligreen is a technology startup developing safe and effective micro-current devices for a wide range of cosmetic and therapeutic applications. With applications ranging from anti-ageing to wound healing, it develops and sells innovative drug-delivery systems to TIer1 pharmaceutical laboratories medical devices, therapeutics, cosmetics, and skincare

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Health Research & Development Center BIONOVEO offers project leaders, whether they are industrial or academic, the skills and biological, technical and methodological resources necessary for the development of new therapeutic and diagnostic strategies, as well as their production processes.

169 similar entities Type: SMB Activities: deeptech Technologies: Synthetic Biology

Galvani Bioelectronics is a joint venture between GSK and Verily Life Sciences. We are devoted to the development of life changing neuromodulation therapies for patients with chronic disease. Medical Devices

103 similar entities Type: SMB Activities: deeptech healthtech Technologies: Synthetic Biology

Inscripta merged with Manus in April 2025 to establish a unique end-to-end platform for scalable development, biomanufacturing, and commercialization of bioalternative products. By combining Inscripta’s advanced whole-genome engineering technologies with Manus’ proven cell factory engineering platform, biomanufacturing expertise, and commercialization capabilities, the merged company – Manus – is uniquely positioned to deliver commercial momentum and scaled profitability in next-generation industrial biotechnology.

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Improving health and life for people living with diabetes, obesity and other cardiometabolic diseases Arecor is a clinical-stage biotech company, developing superior therapeutics that can reduce treatment burden and improve outcomes for people living with diabetes, obesity and other cardiometabolic diseases. Superior Products for Diabetes Treatment, Liquid Products with Superior Stability, Lyo-to-liquid switch, IV to SC switch, High Concentration mAbs, Ready-to-Use (RTU) Formats, Differentiated Biosimilars, Vaccine Stability, and Oral Delivery of Peptides

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BIOMOLECULES NOW, FOR YOUR FUTURE KYLYS is a Life Science Spin-off from the University of Geneva, now ready to step into clinical development. Passionate about science and biotechnology, we are committed to developing a unique technology to deliver highly effective and safe products based on the next generation of hyaluronic acid (HA). Our products are aesthetic (KYLYS Aesthetics) and medical (KYLYS). Our technology can revolutionize HA delivery for medical and surgical needs, in the field of: Aesthetic Rheumatology Reconstructive surgery Drug delivery system Veterinary

90 similar entities Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology

Pulmonary drug delivery with near 100% efficiency DP Innovations Ltd is a privately held healthcare company based in Woodside, CA. The main activity of the company is the development of an innovative pulmonary drug delivery system called SPRIN. SPRIN provides pharmaceutical companies with an alternative delivery system to needle injection for high-precision drugs, such as insulin, gene therapy, antivirals, etc.

61 similar entities Type: Startup Activities: healthtech Technologies: Synthetic Biology

Breakthrough therapies targeting DNA Damage Response, aiming to cure cancer and inflammation Oxcia AB is a pioneer in oxidative DNA damage and DNA Damage Response (DDR – the body’s way of repairing the damage that occurs to DNA). The two most advanced projects emanating from the O2-DDR technology platform are OXC-101 for cancer and OXC-201 for pulmonary fibrosis. The portfolio also includes exploratory projects, e.g. in psoriasis and non-disclosed discovery projects.

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FoRx Therapeutics is developing therapeutics that exploit the presence of DNA replication stress in human cancers FoRx Therapeutics is a recently incorporated privately-held company based in Basel, Switzerland. It is backed by a syndicate of investors that include the Novartis Venture Fund, Pfizer Ventures, M Ventures, Omega Funds and LSP Venture Capital. FoRx Therapeutics focuses on drugging key molecular targets involved in the DNA Replication Stress, as a new approach in the development of targeted anticancer drugs.

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Aerska is a biotechnology company developing RNA medicines to treat, delay, and prevent diseases of the brain. The company is leveraging advances brain delivery technology to enable targeted delivery of next-generation RNAi therapeutics to the CNS. Aerska is headquartered in Dublin, Ireland, with research operations in Stevenage, UK.

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Memo Therapeutics AG, an Ipsen company, is a late-stage biotech company translating unique human immune responses into superior medicines through the development of best-in-class antibodies to treat viral infections.

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Leading Sustainable Anaesthesia SageTech Medical has developed a safe, sustainable and easy to use circular economy solution that captures, recovers and recycles environmentally harmful waste volatile anaesthetic agents for future reuse. The innovative solution integrates simply, seamlessly and universally into existing anaesthetic equipment, with no need for change in clinical practice.

66 similar entities Type: Startup Activities: deeptech healthtech Technologies: Decarbonization

Pushing the limits of conventional chemotherapy Doxanano is committed to pushing the limits of conventional chemotherapy for patients with solid tumors. Our goal is to significantly increase the selective delivery of chemotherapeutic agents into the tumor whilst dramatically limiting adverse effects on healthy organs. We specialize in harnessing the unique properties of our DXN polymersomes drug delivery platform in combination with the precision of radiotherapy.

77 similar entities Type: Startup Activities: deeptech Technologies: SaaS Synthetic Biology

Automated 3D organoid screening technology We integrate standard assays on chip (eg. CRISPR, T-cell, cytotoxicity) to accelerate drug discovery from target to validation, and advance preclinical predictivity

512 similar entities Type: Startup Activities: biotech deeptech healthtech Technologies: Synthetic Biology

New view for cancer therapeutics Sirius NeoSight is an innovative technological breakthrough company which aims to become a key player in the detection of subclinical neo-cancers, relapses and therapeutic monitoring of patients, thus offering doctors a new perspective on the therapeutic effectiveness implemented. Sirius NeoSight uses breakthrough patented technology from a consortium of academic laboratories with expertise in the field.

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Innovation for your health and well-being. Pharmaceutical company, R&D oriented dedicated to the development and marketing of senolytic compounds, food supplements and drugs against aging, age-related degenerative diseases and cancer.

81 similar entities Type: SMB Activities: deeptech biotech healthtech Technologies: Synthetic Biology

CLARTEIS is a global leader in manufacturing advanced and innovative technologies for the Dermatological market. CLARTEIS team is specialized in developing miniaturized and high quality light-based medical devices to provide to Dermatologists worldwide.

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AbLeads is a young biotech startup developing innovative solutions in Oncology, through the generation of novel, personalized therapeutic antibodies. Learn More on https://ableads.fr Biotechnology, Oncology, Immunotherapy, Therapeutic Antibodies, and Personalized Medicine

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Nevezyne develops its own protein expression systems and offers its expertise in the expression of recombinant proteins, for research programs, for diagnosis in animal and human health Protein Expression, Baculovirus System, Protein Purification, and Bacterial System

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Nano Life Sciences Cementic, is biotech startup (Paris, France/Palo Alto, USA). Specializing in cutting-edge nano-biotechnology solutions with a focus on the dental field. Medtech, Biotech, Dental, Orthopedics, Nanotechnolgies, Stem cells , and Liposomes

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Advanced therapies inspired for you Defymed is a French SME that develops innovative medical devices aimed at treating patients physiologically in order to improve the clinical effectiveness of their treatment as well as their comfort. Defymed is a spin-off of the Centre européen d’étude du Diabète (European center for diabetes studies), which began work on a bioartificial pancreas in 1996. Today, Defymed focuses on diabetes, which is considered to be one of the major epidemics of the 21st century. There are currently two medical devices being developed by Defymed which are at an advanced preclinical trial phase: - #MailPan®: bioartificial …

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Built around safe-by-design concept, Adjuvatis is committed for innovative formulations to improve pharmaceuticals Adjuvatis, a French startup in biotechnology, develops innovative safe-by-design delivery systems to help laboratories and pharmaceutical companies in vaccine formulation as adjuvants and in drug delivery as vectors for oncology, dermatology, infections, etc. Our first technology, called i-Particles®, is based on 200 nm-diameter particles composed of poly-lactic acid only (any surfactant and solvents) for formulation of hydrophobic molecules in the particle core and surface functionalization of peptides. Our second technology, i-LipoP®, consists in i-Particles® covered by lipidic bilayers at their surface for vectorization of nucleic acids and …

100 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

We build high tech equipment supporting end-to-end development and manufacture of cell and gene therapies. We build high tech equipment supporting end-to-end development and manufacture of cell and gene therapies. biotech, medtech, cell therapy, gene therapy, CAR-T, MSC, iPS, ATMP, Tissue Engineering, cell based therapies, biotherapies, RMAT, and Manufacturing

227 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Nano Drug Solutions Revolutionizing neuropathy treatment Development of innovative nanomedicines targeting neuropathies, with a particular focus on hereditary neuropathies such as Charcot-Marie-Tooth disease Biothechnology

150 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Inovative company specialized in the development and manufacture of medical devices EOVE develops and manufactures innovatives products to improve care and quality life with greater freedom for Adult ans Pediatric Patients who suffer from breathing disorders and chronic respiratory diseases.

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Theraonco enhance efficacity of wide range of payload agents and reduces their side effects Thanks to the specific assimilation of patented modified sugars equipped with chemical hooks by the tumoral cells, we can concentrate locally any type of payload through a reaction based on « click » chemistry (Nobel Prize, 2022) with carrier containing payload that “click” on the hooks. We want to use this approach to fight against cancer.

95 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

The ELEMENT Biotechnology is an innovative medical device health company focused on developing new solutions THE ELEMENT Biotechnology is a Medtech company based out of 9, Boulevard Gambetta, 38000, Grenoble, FRANCE Dispositifs médicaux, Biotechnologie, Medtech, Maladies neurodégénératives , Santé, Parkinson, and Innovation

220 similar entities Type: Startup Activities: healthtech deeptech Technologies: Synthetic Biology

Unlocking the power of NIK to transform the future of cancer and autoimmune disease treatment Nikaia Pharmaceuticals, an innovative company dedicated to the discovery and development of cutting-edge therapeutic solutions to improve patients' lives. 🔬💊 Our mission is to push the boundaries of science to deliver novel and effective treatments, focusing on the NIK protein (NF-κB-inducing kinase) and developing molecules capable of blocking its action.

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Nanoparticle-Based Radiopharmaceuticals for Targeted Radiation Delivery to Cancer Cells aKen Medical is a biotechnology company that encapsulates highly potent radioactive materials within stable nanoparticles serving as "guided missiles" that deliver targeted radiation straight to tumors while protecting healthy tissue. Our universal nanoparticle platform is designed to address a wide range of cancers, enabling real-time monitoring and advancing a theranostic approach that paves the way for precision medicine. Radiopharmaceuticals, Targeted therapy, Theranostics, Radiation Therapy, Alphatherapy, Nanotechnology, Cancer Therapy, Biotechnology, Radiotherapy, and Precision Medecine

127 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Distribution of innovative and high value-added medical equipment and devices. SANEVA, a specialist in medical devices with high added value, invites you to discover its range of breast pumps and post-operative and post-traumatic cryotherapy.

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Pain relief at the touch of a finger Ethimedix is a healthcare technology company that offers a patented and pragmatic solution to fight against opioid misuse and dependence. Our flagship product, the SmartBottle, is a secure and efficient alternative to Opioid pills and PCA (PatientControlled Analgesia) pumps, utilizing biometric technology to dispense oral liquid opioids safely.

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Reversing Alzheimer's disease symptoms Neurocia is a medtech developing non-invasive medical device allowing stabilizing and reversing symptoms of Alzheimer's disease Alzheimer's disease and Medtech

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Part of Odyssey Therapeutics Rahko was acquired by Odyssey Therapeutics in 2021. Odyssey Therapeutics is a biotech company pioneering next gen immunomodulators and oncology medicine. Read more: https://odysseytx.com/news/

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Small molecules, life-changing power. Alesta Therapeutics is a pioneering company based in Leiden, Netherlands, dedicated to the development of first-in-class small molecules that target GCN2. Our commitment to advanced, high-quality chemistry has led us to develop a clinical candidate with an extensive pre-GLP toxicology and CMC package.

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3D cell shape + AI to bring the right therapies to the right patients sooner Sentinal4D is an AI-powered cancer drug discovery and development company, with close ties to the Institute of Cancer Research. Sentinal4D represents a collaboration of physics, biology and artificial intelligence to drive novel cancer therapy candidates with a high probability of clinical success. Artificial Intelligence, Computer Vision, Systems Biology, and Drug Discovery

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Company specialized in developing new and advanced materials solutions for skin-interacting medical devices BestHealth4U is a company dedicated to the research and development of new and advanced material technologies for skin-interacting medical devices.

106 similar entities Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology

Advanced Nanotechnologies A nanobiotechnology and smart polymers company. The company is committed to products for several engineering the biomedical sectors, with an emphasis on tissue engineering, drug delivery and functionalized electrospun nanofibers. Nanofaber Srl is the exclusive distributor on the Italian soil of Bioinicia Fluidnatek Slu, leader company in Europe regarding the electrospinning equipment and services. Through its high-specialized division, Nanofaber can offer to its clients premium equipment, services and commercial/technical assistance on the electrospinning and electrospraying technology. nanofibers, SERS, oncoproteins, and nanomechanics

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Follow us at Shionogi Inc. for news about our rare disease research programs https://www.linkedin.com/company/shionogi-inc-/ drug discovery, PDE4D, PDE4B, Fragile X, CTE, Rubinstein-Taybi, traumatic brain injury, Clinical Trials, Fragile X syndrome, Cognition, BPN14770, and Memory Loss

364 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Since its establishment in February 2011, Otsuka Medical Devices Co., Ltd. has focused on developing unique solutions that improve the health and well-being of patients whose medical needs and conditions cannot yet be fulfilled by existing treatment methods. To achieve our aspiration of becoming a pioneer in the medical device industry, we combine global R&D efforts with the technology and drug discovery know-how inherent within the Otsuka group’s heritage.

67 similar entities Type: SMB Activities: healthtech deeptech manufacturing Technologies: Synthetic Biology

Healing Hearts Repairon is an innovative clinical-stage biotech company in Göttingen (Lower Saxony, Germany), developing stem cell-based heart muscle tissue for the treatment of advanced heart failure. The goal is to improve the cardiac function of our seriously ill heart patients so that they can lead a normal life again.

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Arkaïya is a groundbreaking platform developing archaea diagnostics and therapeutics for human health and disease. Archaea strains associated with mother’s milk that promote healthy immune system development

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Beyond LNPs. Beyond the liver. A unique plant-based platform to unlock the potential of RNA therapies beyond vaccination Our mission is to unlock the full therapeutic potential of RNA medicines beyond the limitations of conventional lipid nanoparticles (LNPs) delivery and IVT RNA production systems, especially for in vivo cell-therapy developers. Serendip Innovations is developing a next-generation RNA platform that integrates both RNA manufacturing and targeted delivery beyond the liver. Using a unique plant-based production system and programmable phytovirus-like particles (phytoVLP), we generate functional RNAs directly encapsulated into a proprietary non-viral vector designed for targeted extrahepatic delivery, repeat dosing, and scalable …

77 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

HA is foundamental in ophthalmology. Noxelis is engineering what comes next. Noxelis is a French ophthalmic medical device company dedicated in developing next-generation treatments, including polymers and hyaluronic acid as a cornerstone. Through its technological platform, Noxelis proposes different formulations aimed at improving medical practice and provides ophthalmologists with first-in-class therapies to treat ocular surface diseases. Noxelis was founded by a passionate and determined team to bring innovative technologies to market with one focus: Bring patients' ocular comfort to the next level.

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Bone targeted delivery concept Atlanthera is a drug discovery company focused on bone diseases and bone cancer treatments Our vision: Be the leader in bone-targeted drug delivery to cure bone cancer and metastases Atlanthera can rely on a very high-qualified Team and a worldwide-known experts network Our concept: Bone-targeted delivery of anti-cancer drug www.atlanthera.com Watch our concept in video > https://youtu.be/m3BBWguO6hs Durg discovery, Bone-targeted drug delivery, Bone cancer, and Bone metastases

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Modulating T-regulatory cells to balance immunity Egle Therapeutics has been founded with a vision to become a game changer in the field of immunomodulating T-regulatory cells (Tregs) through the unique concept of Tregs’ starving while specifically targeting the most immunosuppressive ones.

137 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Lymph Flow Matters Lymphatica develops medical devices for treatment of lymphatic diseases. Born in 2017 as a spin-off of 2 leading Swiss universities, our first product is intended to bring a terrific improvement in quality of life for lymphedema patients: LymphoDrain, the first implantable artificial lymphatic vessels, is a medical device intended to recirculate lymph inside the patient body, re-establishing the physiological fluid equilibrium.

75 similar entities Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology

Developing therapeutics for diseases with impaired kidney function ENYO Pharma is a clinical-stage biopharmaceutical company developing innovative therapeutics based on fibrolytic and anti-inflammatory properties for diseases with impaired kidney function. The company is conducting Phase 2 trials with its lead compound Vonafexor in Chronic Kidney Diseases (CKD) and rare kidney disease such as Alport syndrome.

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Gecko Biomedical is a fast-paced medical device company, dedicated to the development of innovative tissue reconstruction solutions. We are leveraging our technology platforms to develop novel solutions to disrupt the field of surgery and positively impact the life of patients.

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Wholly Owned Subsidiary of Eli Lilly and Company Orna Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, is a biotechnology company reshaping RNA therapeutics. We are developing the leading circular RNA technology platform (oRNA®) and unprecedented lipid nanoparticle (LNP) delivery solutions – unlocking the therapeutic possibilities of circular RNA and pioneering the next chapter of safe and effective in vivo therapies for the treatment of disease. Website: www.ornatx.com

92 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Fighting chronic and fatal diseases Tirecat Health is a company developing a family of novel polymers with amazing potential in the healthcare field. We are propelled with purpose to fight chronic and fatal diseases affecting patients worldwide using our revolutionary technology to improve their quality of life. In order to make this purpose a reality, the company is preparing to move towards the clinical phase to demonstrate the astonishing results seen in preclinical trials.

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Deliver on the promise of mRNA by providing a more flexible, cost-effective and sustainable manufacturing solution We are pioneering a revolutionary approach to enhance global healthcare access by simplifing and improving the production of mRNA vaccines and therapies.

66 similar entities Type: Startup Activities: healthtech deeptech Technologies: Decarbonization

EryPharm is a biotech start-up company dedicated to the development and the operation of a large-scale process for the production of Red Blood Cells from stem cells. The technology has been developed by Dr. Luc Douay and his team at the Paris Sorbonne university. You can contact EryPharm through our website: http://erypharm.com/contact.html Or you can contact Loïc Tron directly: www.linkedin.com/in/loictron

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NESA MEDTECH PRIVATE LIMITED is a medical device startup working towards excellence in the Research & Development of Medical devices for emerging countries specifically India, and believes in pursuing business through innovation and technology. This is focused on delivering minimally invasive therapeutic devices innovation to address social and economic burden. NESA MEDTECH is mentored and supported by Department of Biotechnology, Government of India and Karnataka Biotechnology and information technology services.

78 similar entities Type: Incubators & VCs Startup Activities: healthtech deeptech Technologies: Synthetic Biology

Making The Impossible Possible We are redefining scientific possibility with our algorithm-driven technology that produces pristine synthetic DNA molecules, enabling our partners to deliver a new generation of transformative solutions for the health of people and planet.

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Multimodal diagnostic and therapeutic platform for the Neuro ICU Syncath Neurosience is focused on diagnostics and therapeutics for brain edema and elevated intracranial pressure such as in traumatic brain injuries, subarachnoid hemorrhage and intracranial hemorrhage

71 similar entities Type: Startup Activities: deeptech healthtech biotech Technologies: Synthetic Biology SaaS

Dairy Done Differently Imagindairy, a Foodtech company, is addressing the industry bottleneck by integrating deep tech with system biology to develop a commercial and viable animal free protein-based dairy product

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Unlocking New Targets to Transform the Treatment of Neurodegenerative Diseases Unlocking New Targets to Transform the Treatment of Neurodegenerative Diseases neurodegeneration, RNA therapeutics, physiological upregulation, post-transcriptional upregulation, mRNA, ASO, and SINEUP

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Entreprise de dispositif médical de diagnostic in vitro : Noratest® In vitro diagnostic medical device Diagnostic, Innovation, Maladies neurodégénératives, Alzheimer, Neurosciences, Entreprise, and Entrepreneuriat

349 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Accelerating drug discovery to transform patients' lives Effective 11/22/21, Acceleron Pharma Inc. is now a wholly-owned subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA (known as MSD outside the United States and Canada) http://merck.com Biopharmaceuticals, Orphan Disease Therapeutics, Rare Diseases, and Serious Diseases

519 similar entities Type: SMB Activities: deeptech biotech Technologies: Synthetic Biology

Sylentis is an European biotechnological company founded in 2006. Sylentis focuses on researching new therapeutic approaches based on gene silencing. Our company is specialised in developing ophtalmologic therapies via interference RNA, a powerful tool for rational drug design. Most advanced product of the company are treatments for glaucoma and dry eye syndrome. Sylentis is a wholly owned member of PharmaMar (www.pharmamar.com) Gene Sinlencing, siRNA RNAi Drugs, Ophtalmology, Biotechnology, RNAi, R&D, Pharmaceuticals, Bioinformatics, Biotecología, Biotech, Experimental drugs, Glaucoma, Dry eye syndrome, Target Therapies, Production, eyes diseases, RNAi Clinical Trials, Ophthalmology, Licensing, Research, Drug Discovey, and Rational Design

86 similar entities Type: SMB Activities: biotech deeptech Technologies: Synthetic Biology

Unlocking microalgae potential Unlocking microalgae potential ● EIT Food Seedbed Incubator (2023 Cohort) ● "Deeptech" certified by French Public Investment Bank (BPI) #microalgae #alternativeprotein

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Transforming cancer and autoimmune treatments with unique IL-1RAP targeting approaches Advesya is a pioneering and transformative biotechnology company developing therapies for difficult-to-treat cancers. Haematology & Oncology, Antibody Drug Conjugate, Cell Therapy, and Autoimmune

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Genenta Science (Nasdaq: GNTA), which will be renamed as Saentra Forge (Nasdaq: SAEN) About: Genenta Science (Nasdaq: GNTA), which will be renamed as Saentra Forge (Nasdaq: SAEN, pending effectiveness), will be a next-generation strategic consolidator focused on privately held specialized companies operating in Italian national security regulated sectors, with activities spanning cybersecurity, defense, aerospace, and biotechnology/biosecurity. Defence, Cybersecurity, Aerospace, and National Security

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Transformative vascular implants. Addressing major life-threatening diseases, backed by Nobel-winning science. Xeltis is developing artificial vessels and valves that are gradually replaced by patients’ own living healthy tissue. www.xeltis.com

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The network of bioproduction biotherapies integrators (RIBB) aims to coordinate, lead and assist the 8 integrators in the field of biotherapies and bioproduction, labeled as part of the “biotherapies and bioproduction of innovative therapies” (SABB) acceleration strategy so that they can respond to their technological platform missions on behalf of academic or industrial partners, and facilitate the industrialization of their technologies/products. Biotherapies, Bioproduction, Cell Therapy, Gene Therapy, and Extracellular Vesicles

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The first registered vaccine against COVID-19 Sputnik V is the world’s first registered COVID-19 vaccine with proven 91.6% efficacy, based on a human adenoviral vector platform. Registered in over 70 countries.

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Smartox Biotechnology is specialized in peptide research and manufacturing Smartox Biotechnology is specialized in peptide research and engineering. Peptide synthesis, physiology, pharmacology, neuroscience, ion channel research, toxin, venomous animals, and screening library

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Providing cancer patients with a longer and better life Atonco is a clinical-stage radiopharmaceutical company developing innovative radiopharmaceutical products using astatine-211, an alpha-emitting radionuclide for the treatment of cancer. Atonco, founded in 2019, built with an experienced and passionate team, has exclusive global licenses for the use of an innovative proprietary antibody and radiolabeling technology.

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Innovative disease modifying treatment for Parkinson's patients Synuca Therapeutics combines decades of groundbreaking research in P-type ATPases and neuroscience from Aarhus University to propose a novel disease-modifying treatment for patients suffering from Parkinson's Disease and associated disorders. By targeting the SERCA calcium transporter, our first-in-class small molecules salvage the root disease cause by repairing the neuronal calcium imbalances caused by pathological α-Synuclein brain species.

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Targeting CCN signaling to treat fibrosis Tribune Therapeutics is a preclinical biopharmaceutical company building a promising pipeline of novel medicines to treat patients with a wide range of fibrotic diseases.

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Smart active ingredients, safer sun exposure Catalonia Exponential Leader 2023 Roka Furadada’s mission is to reduce the incidence of skin cancer through research, development and production of active ingredients and medical devices, with high efficiency and low toxicologic and environmental impact OUR PURPOSE Roka Furadada wants to help to prevent and reduce the incidence of skin cancer. HOW ARE WE GOING TO DO IT? Developing the first intelligent ultra violet radiation filter: SMART UV, with new molecules that entail therapeutic activity to prevent and treat diseases associated with sun exposure. Cosmetics, Raw Materials , Ingredients, Cosmetic Ingredients, Sunscreen, Sun protection …

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Cell & Gene Therapy: Automated. Scalable. Accessible Limula provides an innovative solution for the production of the most personalised cancer treatments on demand and at scale. Our product is a unique proprietary platform can perform multiple steps of cell therapy manufacturing in a single device, using end-to-end automation and integrated process analytics. Bioproduction, Immunooncology, Cell therapy, Biotechnolgoy, Manufacturing, and CAR-T

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