Transforming cancer and autoimmune treatments with unique IL-1RAP targeting approaches Advesya is a pioneering and transformative biotechnology company developing therapies for difficult-to-treat cancers. Haematology & Oncology, Antibody Drug Conjugate, Cell Therapy, and Autoimmune

439 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Dedicated to developing treatments for rare diseases originated from nonsense mutations Genvade aims to harness the power of nonsense mutation readthrough molecules to develop treatments for some of the most burdensome rare diseases. Our lead compound targets indications include cystic fibrosis, Duchenne muscular dystrophy and other genetic diseases. small molecules, drug discovery and development, rare diseases, nonsense mutation corrector, cystic fibrosis, genetic diseases, oncology, readthrough, and Duchenne

96 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

New Natural & Ethical Anti Inflammatory Pharmaceutical Products Natural Products with Proven Health Claims For PETS. Pomega develops a novel, safe, ethical and non-toxic therapy that retards disease progression by inhibiting cartilage breakdown at an earlier stage. Product is developed by skilled pharmacist under drug standards frame First product coming out the pipeline is Ω-344 Product , a patented fruit extract with strong anti inflammatory properties osteoarthritis , anti inflammatory, fruit extract, inflammation, arthritis, biotech, NSAIDs, pain, animal, dogs, pets, wellness, healthcare, petfood, and cats

13 similar entities Type: Startup Activities: pettech deeptech biotech Technologies: Synthetic Biology

Une entreprise spécialisée dans le développement de thérapies transformatrices ayant un impact sur la longévité. Biophytis SA is a clinical-stage biotechnology company specialized in the development of therapeutics that are aimed at slowing the degenerative processes associated with aging. Our small molecules are aimed at stimulating biological resilience to stress during aging. Ruvembri - in regulatory and clinical phases - is our leading drug candidate is administered orally: • for the treatment of severe respiratory events related to COVID-19 following positive results in Phase 2/3 clinical study (COVA) • for the treatment of reduced mobility in elderly patients with sarcopenia, …

48 similar entities Type: SMB Activities: biotech deeptech Technologies: Synthetic Biology

Interventions for Human Diseases Venture-funded company, discovering and developing oral novel small molecule first-in-class inhibitors of Bach1 (a transcription factor) as transformative potential therapy, globally accessible for patients with sickle cell disease (SCD), renal, cardiometabolic and neurodegenerative and other diseases. Sickle Cell Disease, fetal hemoglobin induction, beta-thalassemia, Renal diseases, cardiometabolic diseases, and neurodegenerative diseases

123 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Targeting Chronic Pain Algonist Biotechnologies is a pre-clinical stage biotechnology company, developing novel small molecule therapeutics for chronic pain. Our mission is to develop drugs with similar potency to opioids but without leading to addiction.

79 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

We developed a new generation of cell therapy products to regenerate articular cartilage damage: Cartibeads Vanarix has developed a new generation of cell therapy to produce high-quality hyaline cartilage mini-grafts, named Cartibeads, which resemble native tissue. Cartibeads are bio-engineered cartilage implant made from allogeneic chondrocytes. When implanted during minimally invasive arthroscopic surgery, Cartibeads can completely self-integrate into cartilage lesions and thus regenerate the tissue. Cartibeads are designed for the treatment of cartilage defects in traumatic and osteoarthritic joints. #cartilagerepair #cartilageregeneration #celltherapy #kneerepair #osteoarthritis

Type: Startup Activities: deeptech Technologies: Synthetic Biology

Addressing the problem of natural repair of soft tissues with injectable 3D scaffolds Volumina Medical is a multi-award-winning start-up active in the field of medical devices supported by a solid network of investors. The company develops breakthrough innovations for plastic and reconstructive surgery. The first product is an implantable polymeric biomaterial and targets the regeneration of soft tissue of the human body which are damaged after tumor excision, genetic malformation or trauma. Implants, Biomaterial, and Regenerative Medicine

102 similar entities Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology

Reshaping rhBMP-2 Perspectives Relieving suffering and improving quality of life with next-generation orthobiologics. Regenerative Medicine, Biomaterials, Medical devices, Drug delivery, biotechnology, BMP2, Programmed Drug Release, and Instructive Tissue Scaffolds

203 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Altach is an NLC venture company. At Altach our goal is to become the gold standard in regenerative cartilage technology. We are building a portfolio of biomimetic cartilage grafts allowing surgeons to repair cartilage defects and restore patient’s quality of life. Altach is developing a portfolio of biomimetic cartilage scaffolds utilising Type II collagen which is the building block of native cartilage. The scaffolds are designed to be used stand alone and in conjunction with other cell based therapies. The implants unique composition create a matrix for the patient’s own cells to migrate into and regenerate the cartilage. Medical Devices, …

7 similar entities Type: Startup Activities: deeptech Technologies: Synthetic Biology

#BeyondInnovation #DermalFiller #CYTOSIAL #AestheticMedicine New ideas, new innovations, new ways of thinking for the medical device industry. We are a pharmaceutical company specialized in the discovery, clinical development, production and commercialization of innovative products in the field of regenerative medicine. At Bioxis Pharmaceuticals, we contribute to transform science into groundbreaking medical device that meet doctors need to improve the health and well-being of their patients in the field of dermatology and aesthetic medicine. Medical Device, Dermatology, Aesthetic, Cosmetic surgery, Regenerative medicine, Ultra-pure chitosan, and Hyaluronic Acid

329 similar entities Type: Startup Activities: healthtech manufacturing deeptech biotech Technologies: Synthetic Biology

TissueGen is a developer of next generation drug delivery technologies. TissueGen solves for unmet needs through the development of transformative drug delivery technologies that reduce treatment burden and improve clinical outcomes. We create life changing treatment modalities for patients and their caregivers, treating both acute and chronic conditions.

70 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Leading biotech in the development of innovative microbiome-based biotherapies YSOPIA Bioscience is a clinical-stage biotech company developing cutting-edge biotherapies based on the gut microbiome. Our goal is to bring safe & efficient solutions to patients with high unmet medical needs. Microbiome, Obesity, Gut modulator, Cardiometabolism, Cardiometabolic diseases, Microbiota, and Gut microbiota

216 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

OssDsign is a developer and global provider of next-generation bone graft-substitute products. OssDsign is a developer and global provider of next generation orthobiologics products. Based on cutting edge material science, the company develops and markets products that support the body's own healing capabilities, giving patients back the life they deserve. Website: www.ossdsign.com Newsroom: https://news.cision.com/ossdsign-ab (Always consult Instructions for Use which accompany the products for complete indications, contraindications, warnings and precautions.) Medical devices, Bone regeneration, Bonegraft, Orthopaedic surgery, Spine surgery, and Orthobiologics

33 similar entities Type: Startup Activities: healthtech deeptech Technologies: Synthetic Biology

Syndivia is committed to enhancing treatment options for cancer patients with solid tumors by leveraging the distinctive properties of targeted DAR1 antibody-drug conjugates, which offer improved tumor penetration, stability, and efficacy. Drug development, Biotechnology, Pharmaceuticals, Antibody-drug conjugates, DAR1 ADC, and ADC

173 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Innovation to enhance bone healing. Our mission is to advance the science of bone regeneration through cutting-edge research and continuous innovation by partnering with researchers and physicians. We provide patients with safe, effective products that treat bone defects and promote healing. Bone regeneration, Orthopaedics, Traumatology, Bone substitute, Innovation, Bone void, Biomimetic and Bioactive bone substitute , and Medical Device

24 similar entities Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology

Tiss’You – Regenerative Company – researches and develops medical devices to upgrade your body’s natural healing ability Tiss'You - Regenerative Company - researches and develops medical devices for regenerative medicine to help doctors and patients with innovative therapeutical solutions. Tiss'You is also a production facility of 850 sqm of which 240 sqm are clean rooms. We have next-generation equipments for R&D, production and quality control; 2 patents, 4 tissue substitutes and 2 point-of-care cell therapy devices. medicina rigenerativa, ricerca e sviluppo, clinica privata, prevenzione, innovazione, ortopedia, chirurgia vascolare, wound healing, lipocell, monocytes, integratori alimentari, regenerative medicine, food supplements, biomaterials, medical …

85 similar entities Type: Startup Activities: deeptech biotech healthtech Technologies: Synthetic Biology

Restoring mobility for a better quality of life 4Moving Biotech is a clinical-stage biopharmaceutical company founded in 2020. We are committed to develop first-in-class breakthrough therapies for the millions of patients suffering from osteoarthritis (OA) in the world. 4Moving Biotech is a subsidiary of 4P-Pharma, an innovation accelerator biotech company. Osteoarthritis, DMOAD, Research and Development, and Biotechnology

24 similar entities Type: Startup Activities: deeptech biotech

Regenerative Medicine - Growth Disregulation - Oncology REGULAXIS is a French innovative biotechnology company based at BIOCITECH the technology park of life science of Paris North area. The company is engaged in the research, development and licensing of innovative synthetic molecules for use in human therapies. Its mission is to grant licenses of innovative molecules in a pharmaceutical company after the establishment of a phase II clinical record. REGULAXIS leads its R&D on its own premises, particularly in regard to biochemical and biological experiments, and keeps the mastery of the chemical synthesis of its therapeutic molecules. The company develops its …

261 similar entities Type: Startup Activities: biotech healthtech Technologies: Synthetic Biology

Developing innovative implantable medical devices for orthopaedic applications Lamina Therapeutics is a pioneering biotechnology company, developing innovative medical devices promoting patient's active live. Lamina’s technology consists of a three-dimensional biodegradable wound dressing with nano-reservoirs including active therapeutics in combination with patient’s own stem cells. This unique multifunctional approach offers a variety of potential applications addressing unmet medical needs in the field of orthopaedics, maxillofacial and periodontal lesions. Lamina’s lead product lamina.ONE, offering a hybrid therapeutic action for the repair of cartilage as well as subchondral bone for a full recovery of the articular function, is expected to enter phase I/II …

Type: Startup Activities: biotech healthtech Technologies: Synthetic Biology

Nano Life Sciences Cementic, founded in 2016, is a pioneering biotech startup with bases in Paris, France, and Palo Alto, USA. Specializing in cutting-edge nano-biotechnology solutions, our focus is on revolutionizing healthcare through innovative applications in dental care, orthopedics, and stem cell research. We leverage new paradigms to address complex health challenges, advancing global health from our dual locations. Medtech, Biotech, Dental, Orthopedics, Nanotechnolgies, Stem cells , and Liposomes

60 similar entities Type: Startup Activities: deeptech Technologies: Synthetic Biology

Developing novel therapies for rare bone diseases Innoskel is a pioneering platform biotechnology company developing therapies for rare bone diseases. Innoskel's first asset is a treatment option for a group of rare skeletal disorders collectively known as type 2 collagenopathies, the most severe of which with symptoms present from birth is Spondyloepiphyseal Dysplasia congenita (SEDc), the second leading cause of dwarfism worldwide. Innoskel’s lead gene therapy asset for SEDc has demonstrated good efficacy in proof-of-concept studies. The company’s fundamental mission is to improve the lives of patients living with rare bone disorders and to answer their unmet needs, keeping their …

16 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Ion channel and GPCR drug discovery using innovative KnotBody technology Maxion uses its innovative KnotBody technology in combination with in vitro display technologies to generate therapeutic candidates against ion channels and GPCR proteins.

212 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Viscosupplements, food supplements and topical gels in RHEUMATOLOGY. As a reference for healthcare professionals since 2005 in France in the field of rheumatology, LABRHA is willing to develop its activity across the globe and become a major actor worldwide. In order to achieve this challenge, we are looking to expand our distributor network to provide practitioners and patients around the world with a complete range of innovative and high quality products, from food supplements to medical devices designed to treat rheumatic disorders and improve quality of life. Rheumatology, Viscosupplement, Topical Gel, Fibromyalgia, Osteoarthritis, Osteoporosis, Hyaluronic Acid, Medical Device, Food Supplements, …

Type: SMB Activities: healthtech deeptech Technologies: Synthetic Biology

Helping you achieve positive outcomes for your patients The world needs you at your best, so we create breakthrough solutions that help you save valuable time and restore patients' lives. Medical products and solutions, Dental and orthodontic supplies, and Health information solutions

177 similar entities Type: SMB Activities: healthtech Technologies: Synthetic Biology

"Simplicity, the ultimate sophistication" (Leonardo da Vinci) X-Bolt brings simplicity and efficiency to trauma surgery, whilst improving quality of life for patients. surgery, orthopedics, medical devices, distribution, hip trauma, sales, marketing, and design

104 similar entities Type: SMB Activities: healthtech deeptech Technologies: Synthetic Biology

Building on innovative science to create treatments for patients in need ResoTher Pharma ApS is a biotechnology company focused on developing novel and effective peptide therapeutics for cardiovascular disease by targeting inflammation. Biotechnology, Drug Development, and Pharmaceutical Industry

749 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Agomab is translating a deep expertise in growth factor biology to pioneer and develop novel treatments that aim to resolve fibrosis, repair tissue structure and restore organ function. Combining new scientific insights with robust drug development and a long-term corporate vision, we are building a broad clinical pipeline of differentiated programs with disease modifying potential in severe organ failure and fibrotic diseases.

145 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Fighting chronic and fatal diseases Tirecat Health is a company developing a family of novel polymers with amazing potential in the healthcare field. We are propelled with purpose to fight chronic and fatal diseases affecting patients worldwide using our revolutionary technology to improve their quality of life. In order to make this purpose a reality, the company is preparing to move towards the clinical phase to demonstrate the astonishing results seen in preclinical trials.

114 similar entities Type: Startup Activities: healthtech deeptech Technologies: Synthetic Biology

Unlocking New Targets to Transform the Treatment of Neurodegenerative Diseases Unlocking New Targets to Transform the Treatment of Neurodegenerative Diseases neurodegeneration, RNA therapeutics, physiological upregulation, post-transcriptional upregulation, mRNA, ASO, and SINEUP

322 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Peptide-based therapeutics for treating peripheral pain conditions At Akasi Pharma, we are developing novel peptide-based therapeutics to treat peripheral pain conditions Peptide therapeutics and Peripheral Neuropathic Pain

160 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Bringing precision to the power of biologics with pioneering use of synthetic nanoclays for regenerative medicine. Renovos Biologics Ltd. (Renovos) is a biotech/medtech company focussed on the development of its patented synthetic nanoclay, RENOVITE®, as a drug delivery platform for regenerative medicine and beyond. Regenerative Medicine, Biomaterials, Drug Delivery, Medical Devices, Pharmaceuticals, Stem Cells, Orthopaedics, and Biotechnology

116 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Belgium biotech company providing unique pipeline of medical devices in OsteoArthritis, skin aging and ophthalmology. Capitalizing on a history of innovation and expertise in exclusive natural chitosan chemistry, KiOmed Pharma, a spinout from KitoZyme, develops a unique pipeline of medical devices that address unmet medical needs in high impact pathologies and major social burdens such as invalidating OsteoArthritis, skin aging and ophthalmology. Medical Devices & Implants, Biomaterials, Rheumatology & Joint Health, Dermatology, Biosurgery, Regenerative Medicine, Ultrapure Chitosan, and Animal-free Chitosan

86 similar entities Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology

Regenerative Biomedical Technology Allegro designs and develops a breakthrough biomedical technology for the treatment of chronic degenerative diseases in the field of musculoskeletal disease and neuroscience. Orthopaedics, Neuroscience, Rheumatology, Biopolymers, Life Sciences, Biotech, Manufacturing, and R&D

55 similar entities Type: Startup Activities: deeptech biotech

Aiming to provide improved treatments for chronic respiratory diseases through new, innovative drug substances -

435 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

New therapeutic targets based on arsenic trioxide (As2O3) Founded in 2010, MEDSENIC is a biopharmaceutical start-up that aims to exploit the new possibilities offered by the therapeutic use of arsenic trioxide (As2O3) and thereby provide a treatment for patients with autoimmune diseases. santé, biotechnologies, bioparma, biopharmaceutical, biotech, health, biotechnology, autoimmune diseases, and maladies auto-immunes

375 similar entities Type: SMB Activities: deeptech biotech Technologies: Synthetic Biology

Revolutionizing drug delivery HHC medical is a health tech startup developing a platform technology for targeted and non-invasive drug delivery via wireless electroporation. Drug Delivery, Genetic therapies, and Enabling life-altering therapies

460 similar entities Type: Startup Activities: deeptech healthtech biotech Technologies: Synthetic Biology

Treating Neurodegenerative Disease by Restoring Autophagy At Samsara Therapeutics, we’re on a mission to unlock the full potential of autophagy activation in combating age-related neurodegenerative diseases. Our innovative approach aims to delay the progression of several debilitating conditions, offering new possibilities for patients and their families. biotechnology, biopharmaceuticals, rare disease, neurodegeneration, longevity, drug discovery, and drug development

183 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Better Technology. Better Delivery. Developing a new generation of disease-modifying therapies. Driven by our proprietary Enhanced Delivery Oligonucleotide (EDO) platform, we are creating a pipeline of disease-modifying therapeutics with the potential to safely and effectively target the root cause of serious genetic neuromuscular and neurological disorders. Biotechnology, Chemistry, Biology, Bioscience, Life sciences, and Therapeutics

505 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Innovation in medical needs. Inmedical Therapeutics es un fabricante de productos médicos y soluciones en formato hidrogel ubicado en Vitoria. Biotecnología, Endoscopia, Farmacéutica, and Producto Médico

125 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Making Regenerative Medicine Accessible Roumai Medical is developing next-generation biotechnologies in regenerative medicine and human-machine interface to meet the unmet clinical needs of millions of patients worldwide.

462 similar entities Type: Startup Activities: healthtech deeptech Technologies: Synthetic Biology

Novel small-molecule drugs in immunology, fibrosis and women health Clinical-stage biotech company founded by serial entrepreneurs and owned by private & institutional investors. Discovery and development of new chemical entities with strong IP and worldwide rights targeting indications with high unmet medical need in immunology, fibrosis and women health. Medicinal Chemistry, in vitro Pharmacology, Drug Discovery and Development, Inflammation and autoimmune diseases, IP generation, IBD, Ulcerative Colitis, Crohn's disease, Fibrosis, and Uterine fibroids

265 similar entities Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology

Innovating to Enhance Quality of Life Fitabeo Therapeutics is a clinical-stage specialty pharmaceutical company that develops and commercialises a differentiated portfolio of innovative medicines focusing on indications where existing treatments are inadequate for the target population. It deploys breakthrough technologies to develop medicines that enable patient autonomy, decentralise patient care and provide superior health outcomes. Oral Thin Films, Geriatrics, Paediatrics, Patient autonomy, Equitable Access, Innovative medicines, Medication adherence, Central Nervous System, Women's Health, and Neurology

352 similar entities Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology

Harnessing the healing potential of adenosine for tissue regeneration Privately held company focused on developing and marketing first-in-class regenerative therapies for osteoarthritis. Our proprietary platform technology harnesses the healing potential of the purinergic system which plays a critical role in maintaining cartilage homeostasis. Our lead product is a proprietary formulation for regenerating cartilage in joints with established osteoarthritis, targeting a rapidly growing joint preservation market. Our goal is to offer patients a disease modifying therapy with uncompromising efficacy relative to existing technologies. By developing this disease modifying therapy, we will significantly improve clinical outcomes and patient quality of life, and …

28 similar entities Type: Startup Activities: biotech deeptech healthtech Technologies: Synthetic Biology

We’re changing the way the world treats inflammation and the way the pharma industry treats humanity Join the revolution! We’re changing the way the world treats inflammation and the way the pharma industry treats humanity. Invest today → https://wefunder.com/senjam Sen-Jam's Global scientists have developed a multi-indication patent and FDA-pending product for the prevention of pain and flu-like symptoms for indications not currently being addressed by the FDA OTC Drug Monograph. It's time for a stronger, more resilient world, free of side-effects and filled with living remarkably Inflammation , Wellbeing, Pain Relief, pharmaceutical, and healthcare

16 similar entities Type: Startup Activities: deeptech healthtech biotech Technologies: Synthetic Biology

The Cell Therapy Venture Builder MedXCell is a European cell therapy venture builder with a strong industrial mindset and a global perspective. Our focus is on technologies, techniques or novel applications in major diseases such as cancer, autoimmune, neurological and degenerative disorders. Established in 2018, we have offices in Switzerland, the EU (France) and the US (Cambridge, MA) and a multidisciplinary expert team with entrepreneurial, clinical, operational, business development and funding capabilities. Biotechnology, Cell Therapy, Immunotherapy, NK Cells, Mesenchymal Stromal Cells, Immuno-oncology, and Osteoarthritis

434 similar entities Type: SMB Activities: biotech deeptech Technologies: Synthetic Biology

Transformative vascular implants. Addressing major life-threatening diseases, backed by Nobel-winning science. Xeltis is developing artificial vessels and valves that are gradually replaced by patients’ own living healthy tissue. www.xeltis.com

10 similar entities Type: SMB Activities: healthtech deeptech Technologies: Synthetic Biology

New solutions for autoimmune, inflammatory and bone diseases. BioSenic is an innovative company with the objective of addressing important unmet medical needs in the areas of immunity, auto-immune diseases and organ repair. Cell therapy, Bone and joint tissue regeneration, Osteo-Articular Diseases, autoimmunity, immunity, autoimmune disease, and arsenic

78 similar entities Type: SMB Activities: deeptech biotech Technologies: Synthetic Biology