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CADTH Canada’s Drug and Health Technology Agency. As of May 1, 2024, CADTH is now Canada's Drug Agency. Please follow our new LinkedIn page at linkedin.com/company/cda-amc, as this page will no longer be updated or monitored. Health research, Health technology assessment, Economic evaluation of health technologies, Knowledge mobilization, Cost-effectiveness analysis, Critical appraisal, Network meta-analysis, Systematic reviews, and Patient engagement Type: SMB Activities: healthtech Technologies: Synthetic Biology | 5 | 1 | 4 | 213 | |
Radius Health, Inc. We are a biopharmaceutical company dedicated?to transforming the future for underserved, global patient populations in bone health and related areas. We consistently embrace opportunities to improve the lives of our patients, their caregivers, our communities, our partners, and each other. Type: SMB Activities: healthtech deeptech Technologies: Synthetic Biology | 3 | 0 | 1 | 309 | |
PsychoGenics Discover Your Next Breakthrough PsychoGenics is a preclinical CRO with expertise in CNS and orphan disorders. Our mission is to provide the best validated disease models and comprehensive preclinical capabilities to help companies discover the next generation of treatments for severely disabling CNS and orphan disorders, and reduce the attrition rate in clinical development. We are known for our cutting-edge translational approach to research, our customized solutions, the breadth and quality of our work, as well as for our ability to identify statistically relevant phenotypic changes that help our clients quantify the efficacy of their treatments before they move into … Type: SMB Activities: biotech deeptech Technologies: Synthetic Biology | 0 | 0 | 0 | 146 | |
Cerba Research Transforming Research, Advancing Health Together At Cerba Research we provide world-class clinical research to help life science companies successfully develop the predictive and precision medicines of the future and help people live healthier lives. We are committed to delivering the next generation of healthcare by transforming research and advancing health together. We support you with industry-leading excellence in oncology, virology, vaccine development, immunology, and cell and gene therapy, together with world-class deep specialty testing, from next generation sequencing to flow cytometry, molecular diagnostics, IHC & and spatial Omics, and bioinformatics. We are committed to helping you deliver the next generation … Type: SMB Activities: biotech deeptech healthtech Technologies: Data Analytics Synthetic Biology | 5 | 2 | 2 | 643 | |
BioCryst Pharmaceuticals, Inc. We develop oral small-molecule and protein therapeutics to treat hereditary angioedema (HAE) and other rare diseases. BioCryst Pharmaceuticals is a global biotechnology company with a deep commitment to improving the lives of people living with hereditary angioedema (HAE) and other rare diseases. We leverage our expertise in structure-guided drug design to develop first-in-class or best-in-class oral small-molecule and protein therapeutics to target difficult-to-treat diseases. We are a commercial-stage biotech company with US headquarters in Durham, North Carolina. Our European headquarters is in Dublin, Ireland, and our Discovery Center of Excellence is rooted in Birmingham, Alabama, with many other regional offices … Type: SMB Activities: biotech deeptech Technologies: Synthetic Biology | 3 | 0 | 0 | 591 | |
CMIC Group More than 80% of new drug development in Japan is supported by CMIC'S efforts. 実は、日本の新薬誕生の約8割に、私たちシミックの力が活かされています。 Voted Best Contract Research Organization (CRO) 2024 by Citeline CMIC Group was the first company to provide CRO (contract research organization) services in Japan. Relevant laws and rules had not been established when the group was first established. The CRO Study Group (which later became the Japan CRO Association) was formed by Mr. Kazuo Nakamura, the current CEO of CMIC Group, and others to conduct promotion and public relations activities and to negotiate with the authorities for the establishment of CROs in Japan. CMIC Group … Type: SMB Activities: deeptech biotech healthtech Technologies: Synthetic Biology | 1 | 0 | 0 | 381 | |
SVAS Biosana S.p.A. Health is wealth SVAS Biosana S.p.A. is an Italian Hospital and Health Care company. SVAS Biosana was founded in 1972 and specializes in the distribution of medical appliances. Thanks to the commitment of its Management, this company has been progressively growing and in a few years it has become an important reference point, in Italy and abroad, for the sanitary field. Over time, our society developed an “industrial” project by obtaining the technical skills required to manufacture products under its own brand. The project is achieved through the gradual foundation of different production lines intended to specific articles: Farmex "Incontinence … Type: SMB Activities: healthtech deeptech manufacturing Technologies: Synthetic Biology | 0 | 0 | 0 | 119 | |
LETI Pharma Committed to the patient's health and wellbeing since 1919 LETI Pharma, the Experimental Laboratory for Immunogenic Therapeutics, is an independent, family-owned, biopharmaceutical company. Since its creation, in 1919, LETI Pharma has been working in immunotherapy based on the use of allergens, applying principals of personalized medicine, and a patient approach keeping with the “One Health” philosophy. LETIPharma integrates two lines of business, and several areas of work: HUMAN HEALTH - Immunology and Allergy, centered on the production of allergen extracts for allergy diagnosis and treatment. - Dermatology and skin care, which centers its activity on the development of dermo-pharmaceutical products … Type: SMB Activities: pettech biotech deeptech healthtech Technologies: Synthetic Biology | 0 | 0 | 0 | 572 | |
Laboratorios Rubió More than 55 years working to ensure people have access to their medications, regardless of prevalence. For over 50 years, we have worked to ensure that everyone has access to our medications, regardless of their prevalence, thus improving their quality of life. #WeAreRubió Laboratorios Rubió was founded in 1968 with the goal of marketing medications that, at the time, were not available in our country because they were treatments for low-prevalence diseases. As pioneers in the first drug in Spain for the treatment of ADHD, today we have more than a dozen medications on the market, many of which are … Type: SMB Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 172 | |
Phost'in Therapeutics Unmask Cancer, Elicit Immune Response Phost’in Therapeutics discovers and develops First-In-Class Glycocalyx Modifiers for selective treatment of cancers and other serious diseases. A new and innovative player in the field of Glyco-Immuno-Oncology, Phost’in Therapeutics develops a class of highly potent anti-cancer NCEs (new chemical entities) targeting a key glycosylation mechanism responsible for suppressing the immune response. Our first generation of Glycosylation inhibitors aims to unblock immune response and down-modulate invasiveness for the treatment of aggressive solid tumors. Glyco Immuno Oncology Type: SMB Activities: biotech deeptech Technologies: Synthetic Biology | 11 | 6 | 7 | 14 | |
PHARMAOUEST PRÉVENTIX [Automatic translation follows] French manufacturer of medical devices for home care and nursing homes. Pharmaouest Industries, a French manufacturer of medical devices for home care and nursing homes, is today one of the leaders in pressure ulcer prevention aids. After 40 years of existence, owned entirely by family capital, Pharmaouest Industries offers a very wide range for: • home care • the community With a view to constant progress, Pharmaouest Industries has strengthened its technical and commercial skills with the successive acquisitions of the companies MEDIMO in 2004, BARTEX in 2010 and PRÉVENTIX in 2016. Type: SMB Activities: consumer services healthtech manufacturing Technologies: Synthetic Biology | 1 | 1 | 0 | 22 | |
OptimHal-ProtecSom Inspired by your breath® 💡 French designer of medical devices in the fields of asthma and allergy 📍 Normandy, France 🎓 Company certified ISO 13485:2016, medical device standard The Laboratory OptimHal-ProtecSom is a Norman research SME (Small and Medium-sized Businesses) which designs and manufactures in France medical devices for the lung deposition of medicine, asthma and allergy. The company, which dedicates a third of its resources directly to research, expands in part through an assertive politic of partnership: - Partnerships for the distribution of its devices, currently available in 30 countries through a network of 15 exclusive partners. - Partnerships … Type: SMB Activities: deeptech healthtech manufacturing Technologies: Synthetic Biology | 9 | 3 | 3 | 27 | |
GROUPE JBT [Automatic translation follows] Let's build tomorrow's medical devices together JBT Group specializes in the design and manufacture of molds and the injection of technical plastic parts for the industrial and medical sectors. A family business with 60 years of experience, a leader in the high-tech tooling and injected products segments for medical and pharmaceutical applications, the Group is constantly developing. Employing 700 employees, the Group achieves a turnover of nearly 90 million euros. Managed from the historic site of Molinges, in the Jura, the strategic and development activities serve all 4 French sites and 3 international sites. Today, the Group … Type: SMB Activities: deeptech healthtech Technologies: Synthetic Biology | 1 | 1 | 0 | 76 | |
Salvia BioElectronics Giving people with migraine a better life | Medical device company pioneering migraine therapy | Located in NL & AUS Our mission is to give people with migraine a better life. As a pioneer in the field of medical devices, Salvia BioElectronics is passionately committed to empower people with migraine to reclaim their lives. Our personalized migraine therapy is tailored to the needs of individual patients. And our ambition doesn’t stop there. With our unique bioelectronic technology, we are also exploring applications for other neurological disorders. Our unwavering commitment is driven by a deep desire to restore hope, health and … Type: Startup Activities: deeptech healthtech biotech Technologies: Synthetic Biology | 2 | 0 | 2 | 51 | |
Misfits Health Boundary Breaking Snacks 🍫🥣 High protein. Plant-powered. Always tasty. Fuel your appetite for the unconventional. The world's tastiest plant-powered snacks 🍫 🌱 100% Vegan 📈 Protein-packed 😇 Low sugar 🌏 Carbon Neutral Type: Startup Activities: deeptech Technologies: Synthetic Biology | 1 | 0 | 1 | 55 | |
Newbury Pharmaceuticals AB Your local champion and alternative partner Newbury Pharmaceuticals was founded in 2020 by Swedish Karl Karlsson. We are rapidly growing and offer a product portfolio of specialty pharma medicines with focus on the Scandinavian markets. The portfolio strategy includes niche and value-added small molecules, products based on peptide technology as well as biosimilars in a variety of therapeutic categories. The portfolio consists of pharmaceuticals from several therapeutic areas with oncology, rare diseases and neurology representing more than 70 percent. The company was listed on Nasdaq First North, February 2022. Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 11 | |
Faron A CLEVER Approach to Fight Cancer. Faron is a clinical stage biopharmaceutical company developing novel treatments for medical conditions with significant unmet needs. Its lead program is bexmarilimab, its investigative precision immunotherapy in Phase I/II development as a novel macrophage checkpoint immunotherapy for patients with hematological malignancies. Bexmarilimab is a novel anti-Clever-1 antibody with the ability to switch immune suppression to immune activation. Faron is based in Turku, Finland and Boston, Massachusetts. Faron is listed on AIM under the ticker ‘FARN’ and Nasdaq First North Growth Market ("Nasdaq First North") under ticker FARON. Drug discovery, Drug development, Pharmaceuticals, Novel treatments … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 0 | 0 | 0 | 44 | |
CombiGene CombiGene’s business concept is to develop effective gene therapies for treatment of difficult-to-treat diseases for which adequate treatment methods are currently lacking. The company intends to take its candidate drugs through the phases of preclinical development and initial clinical studies under its own management, and subsequently continue development and commercialization under its own management or in collaboration with other partners. Founded on the basis of scientific discoveries made at Lund University and the University of Copenhagen, CombiGene has offices at Medicon Village in Lund, Sweden. The company is public and listed on the Swedish marketplace Nasdaq First North and the … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 14 | |
IMIDomics Inc. Discovering and developing the next generation of medicines for immune-mediated inflammatory diseases (IMIDs) IMIDomics is a biotechnology company focused on Patient-Centric drug discovery for immune-mediated inflammatory diseases (IMIDs). Our goal is to discover new and impactful IMID drugs by focusing on carefully selected patients, and stratifying populations to identify those most likely to respond. IMIDomics is powered by a unique Clinical Discovery EngineTM, which integrates and analyzes proprietary clinical, epidemiological and patient-derived biomolecular datasets, generated in partnership with the Vall d’Hebron Institute of Research, to establish a deeper understanding of IMID diseases. By doing so, IMIDomics has identified previously unrecognized … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 2 | 0 | 2 | 23 | |
GlyProVac Exploring novel bacterial glycopeptide antigens to address unmet needs in vaccine development GlyProVac has via its proprietary platform technology, BEMAP, discovered that 1) O-linked protein glycosylation is a surprisingly abundant post translational modification in bacterial, 2) glycoproteins are linked to increased immunogenicity. GlyProVac aim to be the first to explore and exploit this novel class of antigens as candidates for vaccine development. The GlyProVac lead YghJ/SslE/AcfD is a conserved protein with a known biological function and has vaccine potential not only in ETEC but also in UPEC. Using BEMAP, GlyProVac has identified 59 glycosylated residues in YghJ. We are in … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 11 | |
HAWK Biosystems Unveiling protein function in patient samples to discovery breakthrough biomarkers. HAWK Biosystems (formerly FASTBASE Solutions) are a biosystems company founded in Bizkaia by Spanish and British scientists from the Francis Crick Institute in London. We have developed a technology that allows for the discovery and quantification of novel biomarkers within any disease state. Specifically, we can determine with high precision which patients will respond to immune-therapy and can stratify patients for treatment using our assay, QF-Pro®. We offer the QF-Pro® service which can be used to discover and quantify biomarkers in FFPE tissue and cell samples and we also offer … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 4 | 0 | 0 | 22 | |
KLISBio Silk innovation for life sciences KLISBio is a clinical-stage regenerative medicine company. We are developing several innovative technology platforms based entirely on natural silk fibroin, which allow for the creation of various solutions for endogenous tissue repair and regeneration. Silk is one of the most renowned and ancient materials used in medicine. In its raw state, silk consists of two main proteins, sericin and fibroin, with a glue-like layer of sericin coating two singular filaments of fibroin. Silk fibroin is fully biocompatible and promotes cell proliferation by also stimulating in-vivo tissue regeneration. Depending on the technology used, it provides a … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 15 | |
EnteroBiotix Mastering the microbiome, transforming lives® EnteroBiotix is a leading microbiome therapeutics platform company that is focussed on transforming the standard of care for patients battling debilitating diseases and infections linked to disruptions to structure and function of the gut microbiome. Type: Startup Activities: deeptech biotech healthtech Technologies: Synthetic Biology | 1 | 0 | 1 | 53 | |
WIMBA We broke the mold on pet orthotics. We've invented the most advanced, custom-fit, lightest-weight pet orthotics ever — with zero plaster mess involved. Vets can scan, specify, and order WIMBA orthotics right from their smartphones: our Al-powered app scans an animal's limb precisely in just minutes. High-fidelity 3D printing yields durable orthotic devices created exactly to a vet's therapeutic or protective specifications, typically printed within 15 working days and ready for worldwide shipment. Our mission is to help the most pets possible live their best lives with greater mobility. Our team of orthopedic device specialists and veterinary medical experts knew … Type: Startup Activities: pettech transporttech Technologies: Synthetic Biology | 0 | 0 | 0 | 24 | |
Roumai Medical Making Regenerative Medicine Accessible Roumai Medical is developing next-generation biotechnologies in regenerative medicine and human-machine interface to meet the unmet clinical needs of millions of patients worldwide. Type: Startup Activities: healthtech deeptech Technologies: Synthetic Biology | 4 | 1 | 3 | 10 | |
Sable Bio Empowering Discovery: Precision Insights for Safer Drug Targets. Prevent target safety failures with unique data insights and cutting-edge approaches. Better prediction of drug safety could help patients and prevent hugely costly trial failures. Our advanced workflows assess clinical side effects and predict potential risks for drugs in development using a suite of data modalities. Empower your drug development process with our state-of-the-art solutions. Build trust with industry-leading validation across several proof points. Gain deeper insights into target safety, minimize risks, and optimize assay validation strategies. Type: Startup Activities: deeptech biotech Technologies: Data Analytics A.I. Synthetic Biology | 0 | 0 | 0 | 9 | |
Neurescue Saving Hearts and Minds - Cardiovascular devices to improve outcomes for emergency patients Headquartered in Copenhagen, Denmark, Neurescue delivers cardiovascular devices to improve outcomes for emergency patients. The company is dedicated to Saving Hearts and Minds with the first FDA cleared intelligent balloon system. Medical Technology and Medical Devices Type: Startup Activities: healthtech deeptech Technologies: Synthetic Biology | 0 | 0 | 0 | 14 | |
Autolus Therapeutics Focused on the development of precisely targeted, controlled & highly active T cell therapies for cancer Autolus is a CAR T cell therapy company. We are applying our extensive programming capabilities to develop advanced autologous T cell therapies that have the potential to deliver life-changing therapies to patients with cancer and autoimmune diseases. Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 0 | 0 | 0 | 643 | |
Desentum Oy Imagine a world without allergies Desentum is a clinical-stage, research-oriented biopharmaceutical company specialized in developing novel types of allergy immunotherapy products (aka allergy vaccines) that are based on switching the immune system's response to allergens from hypersensitivity to tolerance. We have a unique approach for designing allergy vaccines. By studying the molecular mechanism of the hypersensitivity reaction, we have made discoveries that allow for improved design of vaccines against common types of allergies. Our goal is to provide long-term relief from allergic symptoms with only a few months of treatment, as well as reduce the social and economic burden allergies … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 9 | |
Oxford Cannabinoid Technologies Holdings Plc A biotech company harnessing the therapeutic power of cannabinoids. Oxford Cannabinoid Holdings Plc is the holding company of Oxford Cannabinoid Technologies Ltd, a UK-based biotech company. We want to have a positive impact on the lives of people living with debilitating diseases and conditions and to change the narrative about cannabis for good. OCT has a range of compounds in drug development, including proprietary cannabinoid derivatives, phytocannabinoids and completely new chemical entities (NCEs) that target the endocannabinoid system. This maximises the therapeutic potential of cannabinoids. With experience across pharmaceutical operations, R&D, intellectual property, law and finance, OCT’s team is committed … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 6 | 0 | 1 | 10 | |
PepGen Better Technology. Better Delivery. Developing a new generation of disease-modifying therapies. Driven by our proprietary Enhanced Delivery Oligonucleotide (EDO) platform, we are creating a pipeline of disease-modifying therapeutics with the potential to safely and effectively target the root cause of serious genetic neuromuscular and neurological disorders. Biotechnology, Chemistry, Biology, Bioscience, Life sciences, and Therapeutics Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 1 | 1 | 0 | 85 | |
Orbis Medicines We are developing the future of drug discovery with a platform to discover, develop, and deliver drug candidates for challenging targets. Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 1 | 0 | 1 | 20 | |
AMPLY Discovery Novel Biologics. Designed by Evolution. Discovered by AI. Novel Biologics. Designed by Evolution. Discovered by AI. AMPLY Discovery uses machine learning and synthetic biology to mine vast biological data to discover novel biologic drug and nutraceutical candidates. Using a proprietary in silico and in vitro hybrid platform to discover best-in-class molecules AMPLY is helping tackle some of humankind's greatest challenges such as cancer, MDR infections and metabolic diseases. Based in Belfast, Northern Ireland. Spin out from Queen's University Belfast. Biotechnology, Anti-infectives, Drug Discovery, AI, Machine Learning, Animal Health, Healthcare, Genomics, Metagenomics, Cancer, Biologics, Metabolic Diseases, Natural Drugs, Nutraceuticals, and Bioinformatics Type: Startup Activities: deeptech biotech Technologies: A.I. Synthetic Biology A.I. - Machine Learning | 2 | 0 | 2 | 7 | |
Curve Therapeutics Revolutionary intracellular screening platform enables a new generation of first-in-class drugs. Our mission is to transform the discovery of first-in-class small molecule therapeutics by broadening the landscape of disease targets that can be drugged. Our Microcycle® platform enables direct screening for biologically active hits inside mammalian cells and creates a toolkit for hit-to-lead programmes. We are deploying our innovative platform to build a pipeline of first-in-class small molecules to address high priority, therapeutically relevant cancer targets. Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 2 | 0 | 2 | 32 | |
Noninvasix Sound Insights Noninvasix will be the first company to monitor the severity of sepsis and septic shock non-invasively, enabling clinicians to diagnose and monitor the response to treatment of tissue hypoxia in real time. Incorporating Noninvasix into the ICU workflow allows clinicians to more quickly and accurately diagnose critically ill patients and tailor treatments to improve outcomes. Future developments, enhancements, and evidence will expand our technology's use and clinical impact in other indications and settings. Noninvasix is backed by 15 years of optoacoustic research and more than $6.5 million in research grants. Medical Devices, Optoacoustics, Patient Monitoring, Oximetry, Critical Care, … Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology | 0 | 0 | 0 | 3 | |
Lantern Pharma Inc. (Nasdaq: LTRN) Leveraging Artificial Intelligence to Rescue and Develop Cancer Therapies Lantern Pharma, Inc. is a clinical stage pharmaceutical company developing new classes of precision cancer drugs with novel mechanisms of action, and also rescuing or revitalizing abandoned or failed cancer drugs using machine learning techniques, genomic data and precision oncology trials. Lantern Pharma recognizes that the high cost and low success rates in oncology drug development largely stem from the inability to appropriately stratify patient populations prior to enrollment, and also from the inability to fully elucidate mechanisms of action that can suggest potent combinations. Our approach which leverages our RADR … Type: Startup Activities: biotech deeptech Technologies: A.I. A.I. - Machine Learning Synthetic Biology | 1 | 0 | 1 | 28 | |
GlucoActive Sp. z o.o. A wearable device for non-invasive measurement of blood glucose concentration using spectrophotometric methods. A wearable device for non-invasive measurement of blood glucose concentration using spectrophotometric methods. A device intended for diagnostic, prophylactic purposes, in the process of diabetes treatment and control and for sports applications, diabetes, diabetes care, electronic devices, medical devices, diabetes prevention, diabetes monitoring, diabetes management, medtech, healthcare, and diabetes monitoring Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology | 1 | 0 | 1 | 19 | |
Sequence Bio Discovering the true signals of disease to power life-changing medicines. 90% of drug candidates fail, delaying help for those in need. We’re on a mission to change that with better, faster drug target discovery powered by the Newfoundland founder effect. Biotechnology and Drug Discovery Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 4 | 0 | 3 | 17 | |
BreatheSuite Helping asthma and COPD patients live longer, healthier lives. Medicare Advantage Plans & ACOs have seen their costs grow in COPD by 53% since 2010, because of high admission and readmission rates (22%). More expensive inhalers are not the only solution to curb this trend. Pulmonary Rehabilitation (PR) is a comprehensive intervention including endurance training, behaviour change and patient education which is proven to significantly improve COPD outcomes. Pulmonary Rehab has been around for decades and recommended by global and national guidelines, but less than 2% of COPD patients get access because there is one PR center for every 43,000 … Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology | 1 | 0 | 1 | 20 | |
Dalan Animal Health, Inc. We bring the world transformative animal health solutions supporting a more sustainable future. Dalan's novel platform technology has introduced the world's first-ever honeybee vaccine, marking a pivotal milestone for the industry. Our mission is to safeguard the planet’s most underserved animal species, ensuring their continued well-being for global food security and the overall health of our planet. Type: Startup Activities: pettech healthtech biotech Technologies: Synthetic Biology | 1 | 0 | 1 | 25 | |
Nicoya Our mission is to improve human life by helping scientists succeed. Nicoya is a Canadian biotechnology company dedicated to improving human life by helping scientists succeed. Established in 2012, Nicoya was founded by Ryan Denomme in his relentless pursuit to use nanotechnology to increase the affordability and ease of use of scientific instruments. Within 10 years, Nicoya has grown to a team of 100+ employees who have extensive experience working at the forefront of nanotechnology and biotechnology sectors. Nicoya develops innovative and accessible biosensor technology for in-depth characterization of biomolecular interactions. Alto, the world’s first digital high-throughput benchtop SPR instrument, … Type: Startup Activities: nanotech biotech deeptech Technologies: Synthetic Biology | 3 | 0 | 3 | 103 | |
Fuse Vectors Catalyzing Gene Therapy | Revolutionary Technology for Revolutionary Therapies At Fuse Vectors, our mission is to revolutionize AAV gene therapy development. Traditional cell-based technologies have hindered progress, posing challenges in safety, efficacy, development time, and cost. Our Cell-Free AAV technology surpasses these methods, producing safer, more effective, and cost-efficient AAV viral vectors in a fraction of the time. Type: Startup Activities: deeptech Technologies: Synthetic Biology | 0 | 0 | 0 | 11 | |
Pear Bio Patient-centered cancer precision medicine Pear Bio analyzes patient tumor samples and data with a proprietary computational biology platform to deconvolute complex cancer biology and drive patient-centric functional precision medicine and drug discovery. Our ultimate goal is to optimally allocate approved treatments to cancer patients who will benefit from them, while creating novel therapies that are purpose-designed for patients who don't respond to available treatments. The platform uses microphysiological systems and 3D computer vision to measure cancer progression over time. Pear Bio cultures patient tumor samples with matched blood into 3D immune-microtumors to test potential treatment options and combinations ex vivo. … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 3 | 1 | 0 | 36 | |
BioCorteX We believe that everyone - irrespective of who they are or where they live - deserve medications that work We believe that everyone - irrespective of who they are or where they live - deserve medications that work Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 1 | 1 | 0 | 15 | |
MEDIBIOFARMA SL To make disease-modifying treatments available to patients with serious or life-threatening conditions Medibiofarma S.L is a clinical-stage biotechnology company founded in 2016 by a group of professionals with extensive experience in Drug Discovery in the pharmaceutical industry. We aim to generate innovative and high quality research programs based on the modulation of clinically validated therapeutic targets for the treatment of cancer and non-cancer diseases. Medicinal Chemistry, in vitro Pharmacology, Drug Discovery and Development, IP generation, IBD (Colitis, Crohn), Oncology, CNS, and Synaptopathies Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 8 | |
Modus Therapeutics Holding AB We develop sevuparin to help patients with severe conditions and high unmet medical need. Modus Therapeutics is a Swedish biotech company developing sevuparin for diseases with high unmet medical need. The Company’s near-term focus is to develop sevuparin for patients with sepsis/septic shock, a severe and often fatal condition. Sepsis, Systemic inflammation, Heparinoids, Pharmaceutical development, and Pharmaceutical research Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 0 | 0 | 0 | 4 | |
HOOKIPA Pharma Inc. Supercharging Immunotherapy At HOOKIPA, we envision a world in which cancers and infectious diseases can be chronically managed or eradicated. HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company advancing the field of immunotherapy through the development of new immunotherapies based on our proprietary arenavirus platform, which is designed to mobilize and amplify targeted T cells and thereby fight or prevent serious disease. Our pipeline includes wholly owned investigational arenaviral immunotherapies targeting HPV16+ cancers, prostate cancer, KRAS-mutated cancers (including colorectal, pancreatic and lung), and other undisclosed programs. In addition, HOOKIPA aims to develop functional cures for HBV and HIV … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 4 | 1 | 3 | 124 | |
Blackfrog Technologies Design & Manufacture of Emvólio- A portable medical-grade refrigeration system. Blackfrog Technologies Pvt. Ltd. is a Manipal, KA based technology startup company that seeks to improve the efficiency of immunization supply chains. We have developed a patented system for precision cold-chain and vaccine traceability with support from BIRAC (DBT) and leading impact investors in the nation including Venture Centre (NCL, Pune) and Social Alpha to provide logistical support in the last-mile delivery of vaccines. Emvólio is a portable, battery-powered refrigeration device that will strictly maintain any preset temperature for over 12 hours for last mile transport of vaccines. Emvólio’s 2-litre … Type: Startup Activities: deeptech healthtech manufacturing Technologies: Synthetic Biology | 2 | 0 | 2 | 41 | |
Spring Loaded Technology Getting People Back to Doing More of What They Love At Spring Loaded, we've developed the world's first bracing solution that addresses patellofemoral pain and multi-compartment osteoarthritis. Our Spring Loaded technology absorbs the pressure from the painful joint during knee flexion and transfers those forces to the back of the leg during extension. Immediate relief that is changing OA bracing and improving patient outcomes. Movement Kinematics, Bracing, Medical Device, Knee Pain, Arthritis, Osteoarthritis, Biomechanics, and Springs Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology | 1 | 0 | 1 | 16 | |
InnaVirVax InnaVirVax is a French privately-owned biopharmaceutical company dedicated to the development of a cutting edge discovery in the field of therapy/prevention and prognostic of AIDS and HIV infection, other infectious diseases, and cancer therapies. InnaVirVax is developing product candidates resulting from a beakthrough discovery, made at Inserm, the French Medical research council, the AP-HP, the largest hospital in Europe, and University Pierre et Marie Curie in Paris. Based on a new paradigm (i.e. the understanding of the mechanism responsible for the decline of the CD4+ T lymphocytes (CD4) in HIV-infected patients), the products currently developed by InnaVirVax will allow the … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 0 | 0 | 0 | 0 | |
PrediTox Your genotoxicity R&D partner PrediTox commits to support its clients in evaluating the genotoxic and potentially carcinogenic properties of their compounds. With more than 10 years of expertise in the study of genotoxicity, the PrediTox team will meet your expectations thanks to its innovative technique as soon as possible. Since our assay adapts to any compounds and can be carry out on any type of human cell lines, we are able to offer you personalized studies. Our goal is to provide quality information to our customers to help you in your R&D works or in your various projects, while reducing … Type: Startup Activities: deeptech Technologies: Synthetic Biology | 1 | 0 | 1 | 3 | |
Digital Ease® [Automatic translation follows] Facilitate access to digital technology through scalable leasing You need to finance: > your IT equipment and software, > your video systems, > your communications and telephony equipment, > your medical or laboratory equipment, > your measuring instruments, > your robots and cobots, AGVs, AMRs, exoskeletons, > your industrial equipment, > your handling equipment, > ... Opt for financial leasing DIGITAL EASE facilitates companies' access to technological solutions through scalable leasing solutions adapted to both user companies and solution providers. DIGITAL EASE supports solution providers (manufacturers, distributors, software publishers, integrators, etc.) and in particular start-ups in setting … Type: Startup Activities: it services Technologies: 3D Printing Robotics Synthetic Biology | 6 | 1 | 5 | 1 | |
Lightinderm [Automatic translation follows] Develops innovative technological systems for skin care intended for home use. Lightinderm is a French start-up hosted at the Cochin Hospital in Paris, which develops innovative technological systems for skin care intended for home use. Inspired by dermatological treatments, its multi-patented innovation combines for the first time photobiomodulation, photoactive serum capsules and tissue massages. This unprecedented combination activates the natural regeneration of cells and visibly improves the quality of the skin. 9 years of research - 43 patents - 7 clinical studies Medical Device and Cosmetics Type: Startup Activities: cosmetics deeptech healthtech manufacturing Technologies: Synthetic Biology | 2 | 1 | 1 | 19 | |
Unibiome (Peer To Peer Probiotics) Unibiome develops fermentative microbes that have been engineered to produce vitamins and other healthy compounds and designed to be used with any fermentation-based food to increase its nutritional value. We believe that re-purposing the food microbiome is a game-changing approach to feeding 9 billion people by 2050. Biotechnology, Synthetic Biology, Design, Microbiology, and Food Fortification Type: Startup Activities: biotech foodtech Technologies: Synthetic Biology | 0 | 0 | 0 | 1 | |
CITRAGE, Stratégies nutritionnelles innovantes dédiées à la santé des séniors [Automatic translation follows] CITRAGE is a research and development company in the field of health nutrition. It develops in partnership with the University of Paris Descartes food supplements and oral nutritional supplements intended for people over 50 years old. The two main products are made up of 100% L-Citrulline, a non-protein amino acid, having a direct action on muscle protein synthesis, thus optimizing the use of other amino acids and allowing better maintenance of muscles. - MyoCIT is a food supplement to preserve muscle capital during aging, it is intended for young seniors in prevention of age-related muscle wasting (causing … Type: Startup Activities: silvertech biotech deeptech healthtech Technologies: Synthetic Biology | 0 | 0 | 0 | 7 | |
Theranexus Theranexus is a biopharmaceutical company that develops drug candidates to be used in the treatment of central nervous. Theranexus is an innovative biopharmaceutical company that spun off from the French Alternative Energies and Atomic Energy Commission (CEA). It specializes in the treatment of rare central nervous system disorders and is a pioneer in the development of drug candidates targeting both neurons and glial cells. Theranexus has a unique advanced therapy candidate identification and characterization platform focused on rare neurological disorders and an initial drug candidate in clinical development for Batten disease. Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 12 | 7 | 5 | 14 | |
Pharmanity [Automatic translation follows] PHARMAnity, your local pharmacies 💻 Pharmanity.com allows patients to easily access information from nearby pharmacies registered for free on the search engine: contact details, opening hours, available products and prices, services offered and areas of specialization. 👉 Pharmacies can register for free and list their practical information and all their health-related activities (listing of their medicines, areas of specialization and services (screenings, pharmaceutical interviews). Internet, Pharmacies, Health, and Search engine Type: Startup Activities: healthtech Technologies: Synthetic Biology | 11 | 6 | 7 | 1 | |
InVenis Biotherapies Platelet-derived Regenerative Therapy for CNS Disorders InVenis Biotherapies is a biotech compagny, spin-off from academic laboratory U1172 and Taipei Medical University, developping innovative regenerative therapies based on blood platelet. Thanks to the high therapeutic potential of our product, we target the most severe diseases involving cell death, as the amyotrophic lateral sclerosis. Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 7 | 5 | 1 | 2 | |
MED'INN'Pharma A clinic-ready biotech developing human cell-derived secretome drugs to cure inflammation-related pathologies Med’Inn’Pharma (MIP) is a clinic-ready Biotech company that was founded in 2017 as a spin-off from the French blood bank establishment (EFS) and of the French National Institute of Health (INSERM). MIP is a pioneer in developing a new class disease modifying therapies dedicated to resolve pathologic inflammation in a wide range of degenerative diseases and conditions. Our founders are world leaders in immunology and inflammation-resolution, and have developed a patent protected process to harness bioactive molecules from physiologically conditioned human cells into a stable biologic drug product. … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 4 | 3 | 1 | 5 | |
Cellaven Cell culture automation, simple and affordable, for R&D laboratories Cell culture automation for R&D labs: Affordable, time-saving and easy to use. The Nestor automaton is a plug-and-play device able to culture cells in up to 10 flasks or multiwell plates. It is ultra-compact and portable, with a 2xA4 sheet footprint and a weight below 5 kg. Automate the most time consuming tasks in your cell culture processes, for an investment in the range of any other basic lab equipment (and get a return on your investment within 24 months only). biotechnology, automated cell culture, and 3D cell culture Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 8 | 8 | 0 | 4 | |
TreeFrog Therapeutics Cell Therapy for All TreeFrog Therapeutics is a French-based biotech company aiming to unlock access to cell therapies for millions of patients. TreeFrog Therapeutics is developing a pipeline of therapeutic candidates using proprietary C-Stem technology, allowing for the mass production of induced pluripotent stem cells and their differentiation into ready-to-transplant microtissues with unprecedented scalability and cell quality. Bringing together over 150 biophysicists, cell biologists and bioproduction engineers, TreeFrog Therapeutics raised $82M in 2021 to advance its pipeline of stem cell-based therapies in the field of regenerative medicine with the lead program in Parkinson's Disease. In 2022, the company opened a … Tags: FrenchTech120 FrenchTech2030 Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 49 | 24 | 31 | 166 | |
YSOPIA Bioscience Leading biotech in the development of innovative microbiome-based biotherapies YSOPIA Bioscience is a clinical-stage biotech company developing cutting-edge biotherapies based on the gut microbiome. Our goal is to bring safe & efficient solutions to patients with high unmet medical needs. Microbiome, Obesity, Gut modulator, Cardiometabolism, Cardiometabolic diseases, Microbiota, and Gut microbiota Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 4 | 2 | 3 | 4 | |
CEVIDRA NUCLEAR DECONTAMINATION CEVIDRA CREAM, THE EMERGENCY TREATMENT OF EXTERNAL RADIOLOGICAL AND NUCLEAR SKIN CONTAMINATION. WE SHARE WHAT WE LEARN. Skin contamination is one of the most probable risks in Nuclear Accidental Exposure with release of radioactivity. In this case whether it is major nuclear or radiological incident in Nuclear Power Plant, a Military submarine base, a Nuclear medicine department or a Dirty Bomb, general public, first responders, workers and soldiers will be exposed and contaminated. The possibility of accidents made the development of new decontamination strategies crucial. Cevidra, Pharmaceutical Laboratory, in collaboration with Institute for Radiological Protection and Nuclear Safety (IRSN-French national … Type: Startup Activities: deeptech healthtech manufacturing Technologies: Synthetic Biology | 1 | 1 | 0 | 1 | |
Emagina [Automatic translation follows] Let's give back power to pregnant women Emagina works to provide caregivers with a complete solution, aimed at better supporting patients during pregnancy through a connected medical device. A virtuous path, both for patients and their medical teams. The Emagina medical device was developed with midwives, obstetricians and physiotherapists specialized in the perineum. Childbirth, although natural, is also a sporting feat! It is therefore important to prepare physically and psychologically for this moving experience. Our goal is to reduce the risk of grade 2 and higher tears during childbirth, through perineal education during the last 4 months … Type: Startup Activities: healthtech Technologies: Synthetic Biology | 13 | 6 | 9 | 5 | |
ICTYOPHARMA Animal Health Innovation Based in France, we are an independent veterinary laboratory, expert in 3 fields: - Vaccine adjuvants for all livestock, - Diagnostic solutions for aquaculture, - Contract research and services in aquaculture health (CRO and CMO). Animal health, Adjuvant, Veterinary Adjuvant, CRO, Aquatic animal health, Tilapia, Veterinary diagnostic, Diagnostic, Aquaculture, Vaccine development, R&D, and GMP Type: Startup Activities: pettech healthtech deeptech Technologies: Synthetic Biology | 1 | 0 | 1 | 9 | |
Onami Foods Mouth-watering algae & plant-based seafood 🌊🌱🐟 for all engaged gourmets! 🧜♂️🧜♀️ Onami Foods creates mouth watering algae & plant-based seafood recipes for all engaged gourmets. We propose alternatives & tasteful rediscovery of seafood, less the animal & the pollution. Embrace the wave! 🌊🌱🐟 Alternative Proteins, Seafood, Sustainable economy, Food & Beverage, and Plant based seafood Type: Startup Activities: foodtech Technologies: Synthetic Biology | 12 | 3 | 6 | 7 | |
GutyCare Digital therapeutics & patient monitoring solutions specialized in gastroenterology and immunology We develop Digital Support Programs and Digital Therapeutics for patients suffering from digestive pathologies (IBS, IBD, Cancer...) Type: Startup Activities: healthtech Technologies: Synthetic Biology | 4 | 2 | 2 | 6 | |
Biomaneo, a Shimadzu group company [Automatic translation follows] A Shimadzu group company Biomaneo specializes in the design and marketing of innovative medical analysis kits based on the fine analysis of proteins by mass spectrometry for neonatal screening and the diagnosis of various pathologies in hospital laboratories. Screening and Diagnosis, Mass Spectrometry, Medical Device, and Biological Markers Type: Startup Activities: deeptech healthtech Technologies: Synthetic Biology | 0 | 0 | 0 | 16 | |
4Dcell Smart control of the cell microenvironment - Bioengineered in vitro assays Experts in cell microenvironment control. At the forefront of the new challenges in biology, 4Dcell offers more reliable innovative study models, which are closer to the natural environment of the cell. 4Dcell technologies provide solutions for a myriad of applications. Among them, we highlight models for cancer, immune system, organs such as heart or gut, circulating cells, wound healing, neuronal network, stem cells and genetic disorders such as laminopathy. Years of research have led 4Dcell to develop an innovative 3D cell culture technology that enables the acquisition of more … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 2 | 1 | 1 | 13 | |
Altevax Biotech Altevax is developing a disruptive immunotherapy technology against cancer Altevax is developing a powerful pioneering immunotherapy technology against cancer. Its patented melanin-based technology has been proven in pre-clinical trials to boost an antigen-specific immune response with Cytotoxic T-lymphocytes (CD8+ Killer T cells), the body’s most powerful defenders. The Altevax immunotherapy technology works with a wide range of peptides. The Altevax technology is complementary to other anti-cancer immune technologies, such as anti PD1s. Altevax is developing an immunotherapy against glioblastoma, currently in advanced pre-clinical development, with Phase 1/2a expected in early 2024. Altevax's partnership with Assistance Publique Hôpitaux de Paris and … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 11 | 3 | 5 | 6 | |
AmyPore New target, new paradigm, new strategy that address the root cause of Alzheimer, Parkinson, and other proteinopathies AmyPore is a biotechnology company based around the leading science of Pr. Nouara Yahi (University of Aix-Marseillle) and Pr. Jacques Fantini (University of Aix-Marseille and Institut Universitaire de France). Their expertise in molecular neurosciences has led to the discovery of AmyP53, a first-in-class patented nontoxic molecule which tackles a common mechanism of neurotoxicity shared by Alzheimer and Parkinson diseases. The company applies its pioneering computational discovery platform coupled with high performance lipid-protein and protein-protein binding technology and ultrasensitive Ca2+ amyloid pore reporting assay … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 1 | 1 | 0 | 1 | |
E-PHY-SCIENCE E-PHY-SCIENCE is a service company specialized in In-vivo and In-vitro electrophysiological assays. If you are currently developing a program in CNS disorder, we can help you increase your chances of success. By gathering on the same platform In-Vivo and In-Vitro electrophysiological assays, the E-PHY-SCIENCE team is able to offer you a complete range of studies. These assays can reveal specific abnormalities in many genetic models of human brain disease, as well as the effect of new molecules on normal brain functions. These types of experiment provide insights for new therapies as well as understandings of brain diseases mechanisms. We cover … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 1 | 0 | 0 | 10 | |
ProGeLife [Automatic translation follows] Innovative research solutions for rare diseases Development of drugs for the treatment of rare genetic diseases with premature or accelerated aging Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 9 | |
ATLANTHERA Bone targeted delivery concept Atlanthera is a drug discovery company focused on bone diseases and bone cancer treatments Our vision: Be the leader in bone-targeted drug delivery to cure bone cancer and metastases Atlanthera can rely on a very high-qualified Team and a worldwide-known experts network Our concept: Bone-targeted delivery of anti-cancer drug www.atlanthera.com Watch our concept in video > https://youtu.be/m3BBWguO6hs Durg discovery, Bone-targeted drug delivery, Bone cancer, and Bone metastases Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 2 | 1 | 2 | 10 | |
GOLIVER THERAPEUTICS Repair the liver without graft GOLIVER THERAPEUTICS is a spin-off from the INSERM and University of Nantes (CRTI UMR1064-ITUN-Nantes Hospital), focused on developing cell-based Advanced Therapy Medicinal Products (ATMP) to respond to an urgent unmet medical need in transplantation. GOLIVER THERAPEUTICS aims to become a Worldwide leader inregenerative medicine in providing the first cell-based therapy product for life-threatening liver failures. Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 5 | 1 | 5 | 31 | |
OCRvet Your partner for comparative medicine studies Oncovet Clinical Research (O.C.R.) is an innovative Contract Research Organization specialized in the conception and management of clinical trials on Dogs & Cats models with naturally occurring pathologies for efficacy assessment of drug candidates for Human Health. O.C.R. innovative offer is at the forefront of ethics of research involving animals since Dogs & Cats included in clinical trials benefit from new therapies developed for Human. O.C.R. main therapeutic fields are Oncology, Inflammation, Cardiology & Neurology. O.C.R. proposes to support Pharma & Biotech in furthering their drug development programs (in preclinical & clinical phases) by … Type: Startup Activities: pettech biotech deeptech Technologies: Synthetic Biology | 3 | 1 | 1 | 21 | |
METAFORA biosystems AI-Powered Cytometry & Cell Metabolism Profiling At Metafora, we develop innovative and impactful AI-powered cytometry & cell metabolism profiling solutions. We are passionate about cell biology. We leverage our unique cell metabolism and AI-powered data analysis platforms to turn disruptive single-cell technologies into impactful solutions that improve human health. biomarkeurs, cell metabolism, flow cytometry, data analysis, biotechnology, IVD tests, diagnostics, diagnostic tests, cell biology, neurometabolic diseases, metabolic diseases, oncology, multiple myeloma, and research Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 18 | 2 | 12 | 35 | |
EG 427 Pinpoint Gene Therapy At EG427 our unique, non-replicative Herpes Simplex Virus type 1 (HSV-1) based vector platform delivers, with pinpoint precision, highly selective, durable expression of disease modifying transgenes to address prevalent diseases in neurology. Our lead asset EG110A, for the treatment of neurogenic bladder dysfunction, has received IND clearance in June 2024 from the US FDA. Our revolutionary approach to the treatment of this disease aims at providing patients with a comprehensive, long-term solution to their bladder management, through a highly selective molecular biology approach overcoming the drawbacks of current standard of care. Our HQ and labs are in … Type: Startup Activities: biotech healthtech deeptech Technologies: Synthetic Biology | 2 | 2 | 0 | 23 | |
Rarecells Detect and defeat cancer from its start through a simple blood draw. Rarecells develops and commercializes the ISET technology to isolate Circulating Cancer Cells for early cancer diagnosis and medical research. Rarecells® Diagnostics was created in 2010 by Patrizia Paterlini Brechot, Professor of Cell Biology and Oncology, in order to make the scientific and technological advances developed by her team available to research teams and patients. Rarecells® Diagnostics’ core product is the patented ISET® (Isolation by SizE of Tumor cells) Technology. Rarecells® Diagnostics has the exclusive license of patents belonging to the French Public Institutions University Paris Descartes, Assistance Publique … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 1 | 1 | 0 | 22 | |
Scipio bioscience Single-cell sequencing on every benchtop Scipio bioscience had to cease its operations on 18/09/2024. At Scipio bioscience we were passionate about empowering every researcher to discover the molecular mechanisms of life for better health and a sustainable world. Enabling deeper insights into disease understanding, Scipio wanted to boost the access to and increases the pace of discoveries with its Asteria benchtop kit for easy scRNA-seq sample preparation and its Cytonaut intuitive cloud-based data analysis software for biologists and bioinformaticians alike. Scipio provided all researchers with empowered autonomy to embrace the next step in single-cell, working with unaltered transcriptomic data for … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 4 | 2 | 3 | 14 | |
Innoskel Developing novel therapies for rare bone diseases Innoskel is a pioneering platform biotechnology company developing therapies for rare bone diseases. Innoskel's first asset is a treatment option for a group of rare skeletal disorders collectively known as type 2 collagenopathies, the most severe of which with symptoms present from birth is Spondyloepiphyseal Dysplasia congenita (SEDc), the second leading cause of dwarfism worldwide. Innoskel’s lead gene therapy asset for SEDc has demonstrated good efficacy in proof-of-concept studies. The company’s fundamental mission is to improve the lives of patients living with rare bone disorders and to answer their unmet needs, keeping their … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 8 | 7 | 1 | 7 | |
Affluent Medical [Automatic translation follows] Addressing unmet needs in structural heart disease, vascular therapy and urology. Affluent Medical is a new French medtech player with the ambition of becoming a European leader in the cardiovascular and urological fields. Affluent Medical develops innovative, next-generation, minimally invasive implants to restore essential physiological functions in these fields: - Kardiozis aims to prevent endoleaks and the risk of abdominal aortic aneurysm recurrence, allowing patients to live more peacefully in the face of an unpredictable risk of rupture; - Kalios and Epygon aim to offer more physiological surgical treatments for the repair or replacement of the heart's … Type: Startup Activities: deeptech healthtech manufacturing Technologies: Synthetic Biology | 4 | 2 | 2 | 69 | |
Evora Biosciences First-in-class immunomodulatory peptides. Evora Biosciences develops novel immunomodulatory peptides with the aim to bring first-in-class treatments to patients in areas of high unmet need. immunodermatology, peptides, inflammatory diseases, respiratory diseases, inflammation, and immunomodulation Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 5 | 3 | 2 | 8 | |
Egle Therapeutics Modulating T-regulatory cells to balance immunity Egle Therapeutics has been founded with a vision to become a game changer in the field of immunomodulating T-regulatory cells (Tregs) through the unique concept of Tregs’ starving while specifically targeting the most immunosuppressive ones. Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 2 | 1 | 1 | 38 | |
Step Pharma Developing selective inhibitors of CTPS1 for patients with cancer and auto-immune diseases Step Pharma is the world leader in the discovery and development of inhibitors of CTPS1 (cytidine triphosphate synthase 1) for the treatment of cancer and autoimmune diseases. Step Pharma’s lead program dencatistat (STP938) is a first in class, potent, selective, oral inhibitor of CTPS1 with demonstrated anti-tumor activity. Dencatistat entered clinical development in 2022 in a PhI/II study for the treatment of relapsed and refractory T-cell and B-cell lymphoma. More recently a solid tumour study was started focused on ovarian cancer using the concept of synthetic lethality and … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 1 | 0 | 0 | 16 | |
NUTRIFIZZ [Automatic translation follows] A pioneer, Nutrifizz is a scientific and technical design office that places health nutrition at the heart of research and innovation projects for players in the food chain. Created by two doctors in nutrition, Céline GRYSON and Emilie CHANSEAUME, Nutrifizz is committed to providing depth through science, to engage in future themes in the field of innovation by surrounding itself with the best partners. Our leitmotif: Co-constructing the resolution of the science, regulation, market equation! Beyond their cross-disciplinary knowledge, our project managers have specific scientific expertise in connection with the future challenges of nutrition, such as plant … Type: Startup Activities: healthtech Technologies: Synthetic Biology | 17 | 9 | 11 | 6 | |
MAbSilico The only TechBio providing computationally designed antibodies through AI with biological validations associated MAbSilico is a TechBio company developing and providing AI-based solutions for antibody drug design and discovery. We help biotech and pharma companies to leverage antibody discovery risks by providing computational candidates in days which are designed and characterized in silico and validated with state-of-the-art biological technologies. While MAbSilico combines 3D modeling, interaction simulation and linear sequences analysis, the antibody drug candidates are defined through their epitope, affinity, off-target risk, cross-species reactivity and developability assessment to be ready for biological activity evaluation. Using NLP technologies we gather information … Type: Startup Activities: deeptech biotech Technologies: A.I. A.I. - Natural Language Processing Synthetic Biology | 18 | 5 | 11 | 13 | |
Medical Device Engineering MEDICAL DEVICE ENGINEERING S.A.S to bring innovators the missing link in the development of their medical devices. We created MEDICAL DEVICE ENGINEERING S.A.S to bring innovators the missing link in the development of their medical devices and disposables. The concept of your therapy, or surgery has been proven from the medical point of view (PoC) and you need a device? Or you may simply have an idea and do not know where to start to make it concrete? Our Philosophy: A team composed of both Scientists & Engineers (plastics processing) to better understand each other, and to make … Type: Startup Activities: biotech deeptech healthtech manufacturing Technologies: Synthetic Biology | 0 | 0 | 0 | 3 | |
Pharm'image #Pharmaco-imaging, #nuclear medicine, #PET/MRI, #Radiochemistry, #Preclinical models Created in 2008 in Dijon, Pharm’image is a regional center of excellence in Pharmaco-imaging. Unique in France, it brings together hospitals, biotechnology, and pharmaceutical companies, to offer state-of-the-art of functional and molecular imaging technologies (MRI, PET, SPECT, CT), ranging from small-animal scale for preclinical experimentation to clinical exploitation Its aim is to deploy cutting-edge medical imaging technologies to evaluate biomarkers that can be used to track treatment efficacy and select the active and most promising drug candidates. imaging, preclinical evaluation, pharmacology, molecular imaging, nuclear medicine, radiochemistry, bioconjugation, translational research, in vivo pharmaco-imaging, First … Type: Startup Activities: biotech deeptech healthtech Technologies: Synthetic Biology | 0 | 0 | 0 | 1 | |
SUPERBRANCHE Nanomaterials as Nanomedicines: let's play collective! SUPERBRANCHE : Nanomedicine as a breakthrough to treat cancer We bring answers to the following issue: intratumoral injection of nanomaterials implying both accessibility and detection of the tumor beforehand. We position ourselves as a producer dedicated to the synthesis of architectured nanomaterials as simple as possible and of controlled size. Our modular technology platform presents both therapeutic and diagnosis applications. It consists in a magnetic nanoparticle coated by a tailor made branched architecture. Thanks to their optimized shape and stability, our compounds are well tolerated and can be administered intravenously, thus helping to the … Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 14 | 6 | 7 | 10 | |
PKDERM Smart innovative solutions in dermatology and respiratory diseases Welcome to PKDERM - Your Trusted Partner for In Vitro Safety and Efficacy Solutions. PKDERM is a leading provider of innovative and effective solutions for in vitro efficacy and safety testing of new products. Our team of experts has years of experience in the industry, and we are committed to delivering the highest level of quality and support to our clients. At PKDERM, we specialize in in vitro safety and efficacy testing, using a range of biological models such as 2D and 3D human skin equivalent models, excised human skin, 2D and … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 5 | 2 | 4 | 2 | |
STH BIOTECH Unlocking the access to innovative ingredients and APIs from cannabis, thanks to plant biotechnology. STH BIOTECH develops unique and reliable plant-biotech process to produce cannabinoids at high yield & low cost. Type: Startup Activities: biotech deeptech Technologies: Synthetic Biology | 14 | 6 | 12 | 12 | |
Gene&GreenTK Enzymes for agricultural transition Gene&GreenTK (GGTK) is a biotech company created in 2013 and incubated in the IHU of Marseille. The work of GGTK is dedicated to the development and engineering of innovative enzymes isolated from microorganisms living in extreme environments. Enzymes developed by GGTK have two main applications: - Anti-virulence and anti-biofilm for the development of sustainable alternative to conventional antimicrobial agents targeting applications in agriculture, animal nutrition or anti-fouling. - Bioremediation of organophosphorus chemicals for the degradation of insecticides and chemical warfare agents. enzyme, protein engineering, Quorum quenching, organophosphorus decontamination, bioremediation, anti-fouling, biofilm, bacterial virulence, biocatalysis, extremophiles, lactonase, … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 5 | 1 | 0 | 11 | |
Isomab Ltd IsomAb is taking a different approach to identify, evaluate and develop isoform specific antibodies to treat disease where patients currently have limited or no treatment options. IsomAb is developing isoform specific antibodies and it has identified, using a combined bioinformatics/knowledge-based platform approach, ISM-001 which specifically inhibits the VEGF-A165b isoform of Vascular Endothelial Growth Factor-A (VEGF-A); based on 20 years of research by our two Founders, the evidence shows reducing serum levels of VEGF-A165b is key to ensuring new blood vessel formation in patients with ischemic disease. Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | 14 | |
OMRON Healthcare EMEA Global leader in the field of clinically proven, innovative medical equipment for health monitoring and therapy. Committed to improving people's lives, OMRON Healthcare provides clinically proven, innovative medical equipment for health monitoring and therapy. With over 300 million blood pressure monitors sold, OMRON Healthcare is market leader in digital blood pressure monitors for both home and professional use. Our product portfolio includes blood pressure monitors, nebulizers, electronic thermometers and activity counters as well as body composition monitors and professional medical devices. For many decades, OMRON’s devices have helped people to prevent, treat and manage lifestyle diseases both at home and … Type: SMB Activities: healthtech deeptech Technologies: Synthetic Biology | 3 | 0 | 3 | 215 | |
CENTOGENE The essential biodata life science partner for rare and neurodegenerative diseases CENTOGENE’s mission is to provide data-driven, life-changing answers to patients, physicians, and pharma companies for rare and neurodegenerative diseases. We integrate multiomic technologies with the CENTOGENE Biodatabank – providing dimensional analysis to guide the next generation of precision medicine. Our unique approach enables rapid and reliable diagnosis for patients, supports a more precise physician understanding of disease states, and accelerates and de-risks targeted pharma drug discovery, development, and commercialization. Biochemical diagnostic test, Genetic diagnostic test, Rare diseases, Congenital diseases, Oncogenetics, Clinical and medical interpretation of genetic data, Next Generation … Type: SMB Activities: biotech deeptech Technologies: Synthetic Biology | 25 | 0 | 22 | 429 | |
Just - Evotec Biologics Designing and applying innovative technologies to dramatically expand global access to biotherapeutics. Just – Evotec Biologics, wholly owned by Evotec SE, is a first-to-industry biologics platform that leverages AI/ML technologies and world-leading molecular design, cell line development, process intensification and continuous manufacturing strategies to advance biotherapeutics from discovery through clinical stages to commercial launch. The Just – Evotec Biologics team combines deep industry experience in the fields of data, protein, process, and manufacturing sciences including automation with highly integrated and flexible capabilities to break through the scientific and economic barriers associated with the development of protein therapeutics. Our focus is … Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 6 | 2 | 5 | 579 | |
Maya AI Maya AI is a personalized AI solution designed to enhance team performance and improve customer experience. Maya AI is a personalized AI solution designed to enhance team performance and improve the customer care experience. By combining Workflow Automation and Artificial Intelligence, we make tasks easier and faster, with a special focus on personalizing experiences. This empathic approach builds smarter decisions resulting in customer and team retention, satisfaction, and loyalty. With Maya AI, everything feels more personal, boosting engagement and driving success for the future. Unlock a Smarter Approach to Team Dynamics: https://mayaknows.com/ Customer Experience, Scalable, Personalized, HR, Regulation, and Omnichannel Type: Startup Activities: it services Technologies: A.I. Data Analytics A.I. - Deep Learning A.I. - Natural Language Processing A.I. - Machine Learning Synthetic Biology Generative A.I. | 18 | 1 | 17 | 14 | |
Inmedical Therapeutics Innovation in medical needs. Inmedical Therapeutics es un fabricante de productos médicos y soluciones en formato hidrogel ubicado en Vitoria. Biotecnología, Endoscopia, Farmacéutica, and Producto Médico Type: Startup Activities: deeptech biotech Technologies: Synthetic Biology | 0 | 0 | 0 | N/A | |
Koite Health We contribute to a better quality of life with healthcare solutions enabling improved oral health Koite Health is a Finnish health tech company whose innovation, Lumoral®, has already revolutionized dental care in Finland and is quickly expanding in Europe. Lumoral® is an advanced and patented medical device that treats and prevents oral diseases. The company's expert team is composed of high-level professionals with decades of experience in the medical and pharma industries, marketing, and clinical research. The company's scientific board consists of internationally recognized dental professors and researchers. Lumoral is an oral health device used in addition to regular tooth … Type: Startup Activities: healthtech Technologies: Synthetic Biology | 0 | 0 | 0 | 20 |