PhysioStim
Entity

  • PhysioStim

    Created in 2000

  • Social networks

    1,831

  • Activities

    biotech deeptech

  • Technologies

    Synthetic Biology

  • Entity types

    SMB

  • Location

    10 Rue Henri Regnault, 81100 Castres, France

    Castres

    France

  • Employees

    Scale: 2-10

    Estimated: 10

  • SIREN

    429482557

  • Engaged corporates

    0
    0 0

  • Added in Motherbase

    3 years, 2 months ago
Description
  • Value proposition

    Nonclinical expert in cardiovascular pharmacology & electrophysiology and vascular functions

    PhysioStim is a French preclinical CRO dedicated to cardiovascular pharmacology and electrophysiology from discovery stages to clinical development. Whatever the therapeutic areas, we ensure robust and valuable preclinical data on cardiac and vascular activities and secondary pharmacology to secure in-vivo development and bring new safe therapies to patients. Thanks to our predictive and translational models, we define the POC of drug discovery, we investigate secondary pharmacology with on and off-target liabilities, and we address the safety purpose to build and support your IND submission (with mandatory and not mandatory assays).
    Physiostim senior scientific team is evolving in a GLP environment, the reactivity and accuracy are our best “signature” for more than 20 years.

    Let’s bridge the preclinical gap together, for the success of your clinical applications.


    Pharmaceutical, Biotechnology, Drug Screening, Drug Development, CRO, GLP, R&D, Preclinical Development, cardiovascular Safety Assessment, Cardiac Cellular Electrophysiology, ion channel discovery, In vitro Technology, Ex vivo technology, Patch Clamp, MEA-Impedance, Langendorff, hERG, in vivo, ischemia-reperfusion, heart rate, ischemia myocardial, vascular model, vasoreactivity, and human translationel model

  • Original language

    Nonclinical expert in cardiovascular pharmacology & electrophysiology and vascular functions

    PhysioStim is recognized as one of Europe’s most reliable CROs specializing in pharmacology and electrophysiology on cardiovascular and vascular functions from the earliest stages during drug discovery phase to IND submission with a wide range of assays. Our experts offer electrophysiological studies a, and preclinical resources, as well as their dedicated expertise in answering ICH S7A and S7B guidelines in accordance with GLP. We also respect the 3R principle and have already taken steps to comply with the upcoming CIPA guideline.

    PhysioStim is highly experienced in cardiac SAFETY assessment, from the earliest stages during drug discovery to preclinical regulatory studies under GLP conditions (hERG and telemetry studies). PhysioStim offers a large range of models like ion channel studies, human cardiomyocytes contractility studies, isolated perfused heart experiments, isolated vascular studies, and MEA-Impedance studies

    PhysioStim is performing cardiovascular EFFICACY studies, with a wide range of ex-vivo and in-vivo diseases models (Ischemia-Reperfusion Injury, Post MI-induced Heart failure, acute hemodynamic or electrocardiography) with invasive and non-invasive assays assessing cardiovascular parameters in anesthetized or conscious animals.

  • Preclinical Cardiovascular Expert - PhysioStim

    PhysioStim is a Preclinical Cardiovascular Expert CRO offerering many studies such as: hERG-GLP, cardiac ion channel assays, Langendorff, ...

    • https://www.physiostim.com/
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