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523 Davis Dr, Morrisville, NC 27560, USA
Morrisville
United States of America
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Scale: 51-200
Estimated: 54
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5 years agoLocus Biosciences, Inc. is a biotechnology company that develops CRISPR-engineered precision antibacterial products.
Next generation CRISPR technology for programmed cell death. Focused on developing therapies for infectious disease and the microbiome.
Locus Biosciences’ novel approach to precision antimicrobials works by taking advantage of a part of an immune system present in many bacteria called the CRISPR-Cas system. The CRISPR-Cas system protects bacteria from invaders such as viruses by creating small strands of RNA called CRISPR RNAs, which match DNA sequences specific to a given invader. When the CRISPR RNAs find a match, they activate Cas proteins that cut the DNA.
Locus Biosciences has developed a platform to design and deliver custom CRISPR-Cas systems directly to specific bacteria. Guided by the custom Locus Bio CRISPRs, the Type-I Cas proteins work to destroy bacterial DNA and cause the bacterial targets to “self-destruct”. Locus’ platform enables the development of antimicrobials which avoid currently known resistance mechanisms while leaving non-target bacteria unharmed. Built on prokaryotic technology for prokaryotic targets, Locus is advancing its platform to create therapeutics for critical-need therapeutic areas ranging from resistant bacterial infections to the microbiome.
CRISPR, Bacterial Infections, Antibiotic Resistance, Biotechnology, Microbiome, and Targeted Therapeutics
Precision Medicines for Bacterial Infections and Microbiome Diseases Locus is developing powerful, precision medicines designed to combat the growing
Corporate | Type | Tweets | Articles | |
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GSK Pharmaceutical, Pharmaceutical Manufacturing | GSK Pharmaceutical, Pharmaceutical Manufacturing | Other 19 Nov 2022 | | |
Johnson & Johnson Pharmaceutical, Hospitals and Health Care | Johnson & Johnson Pharmaceutical, Hospitals and Health Care | Not capitalistic Partnership Not event 23 Nov 2022 | |